| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | pirimicarb |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1912459 | Belzunces LP, Colin ME: Differential response of Apis mellifera acetylcholinesterase towards pirimicarb. Neuroreport. 1991 May;2(5):265-8. The kinetic analysis of Apis mellifera acetylcholinesterase inhibition by the pirimicarb showed that native and detergent-solubilized membrane enzyme exhibited slightly different carbamylation kinetics. |
95(1,1,3,5) | Details |
| 15532677 | Benting J, Nauen R: Biochemical evidence that an S431F mutation in acetylcholinesterase-1 of Aphis gossypii mediates resistance to pirimicarb and omethoate. Pest Manag Sci. 2004 Nov;60(11):1051-5. |
82(1,1,1,2) | Details |
| 19413913 | Lu Y, Gao X: Multiple mechanisms responsible for differential susceptibilities of Sitobion avenae (Fabricius) and Rhopalosiphum padi (Linnaeus) to pirimicarb. Bull Entomol Res. 2009 Dec;99(6):611-7. Epub 2009 May 5. Acetylcholinesterase is the target enzyme of pirimicarb and the sensitivity of acetylcholinesterase to pirimicarb was significantly higher in Rhopalosiphum padi than in Sitobion avenae. |
81(1,1,1,1) | Details |
| 494273 | Cambon C, Declume C, Derache R: Effect of the insecticidal derivatives (carbofuran, pirimicarb, aldicarb) on the activity of acetylcholinesterase in tissues from pregnant rats and fetuses. Toxicol Appl Pharmacol. 1979 Jun 30;49(2):203-8. |
81(1,1,1,1) | Details |
| 12210959 | Li F, Han Z: Purification and characterization of acetylcholinesterase from cotton aphid (Aphis gossypii Glover). Arch Insect Biochem Physiol. 2002 Sep;51(1):37-45. The purified AChE was more sensitive to eserine, methamidophos, and pirimicarb. |
20(0,0,2,10) | Details |
| 12915723 | Villatte F, Schulze H, Schmid RD, Bachmann TT: A long insertion reverts the functional effect of a substitution in acetylcholinesterase. Protein Eng. 2003 Jul;16(7):463-5. We introduced incrementally the single substitution W290A and a 26 amino acid long insertion at the 297 location in the Nippostrongylus brasiliensis acetylcholinesterase B sequence and analysed in vitro the induced changes in the hydrolysis rate of three hemi-substrates: pirimicarb, paraoxon methyl and omethoate. |
32(0,1,1,2) | Details |
| 17215041 | Badiou A, Meled M, Belzunces LP: Honeybee Apis mellifera acetylcholinesterase--a biomarker to detect deltamethrin exposure. Ecotoxicol Environ Saf. 2008 Feb;69(2):246-53. Epub 2007 Jan 9. Joined actions of deltamethrin (pyrethroid) and pirimicarb alone or in association, are investigated on AChE activity in surviving and dead honeybees, with a special focus on the relative proportions of its membrane and soluble forms. |
18(0,0,2,8) | Details |
| 18602378 | Badiou A, Belzunces LP: Is acetylcholinesterase a pertinent biomarker to detect exposure of pyrethroids? A study case with deltamethrin. Chem Biol Interact. 2008 Sep 25;175(1-3):406-9. Epub 2008 Jun 13. Joined actions of deltamethrin and pirimicarb alone or in association (dual treatment), were investigated on AChE activity in surviving and dead honeybees in order to test its reliability as biomarker. |
10(0,0,1,5) | Details |
| 15373811 | Toda S, Komazaki S, Tomita T, Kono Y: Two amino acid substitutions in acetylcholinesterase associated with pirimicarb and organophosphorous insecticide resistance in the cotton aphid, Aphis gossypii Glover (Homoptera: Aphididae). Insect Mol Biol. 2004 Oct;13(5):549-53. |
8(0,0,1,3) | Details |
| 12233192 | Mazzoni E, Cravedi P: Analysis of insecticide-resistant Myzus persicae (Sulzer) populations collected in Italian peach orchards. Pest Manag Sci. 2002 Sep;58(9):975-80. In these populations, collected as primary colonies or as secondary ones, total esterase content and acetylcholinesterase sensitivity towards pirimicarb was assessed using biochemical assays. |
7(0,0,1,2) | Details |
| 12849975 | Nabeshima T, Kozaki T, Tomita T, Kono Y: An amino acid substitution on the second acetylcholinesterase in the pirimicarb-resistant strains of the peach potato aphid, Myzus persicae. Biochem Biophys Res Commun. 2003 Jul 18;307(1):15-22. |
7(0,0,1,2) | Details |
| 17546082 | Chen MH, Han ZJ, Qiao XF, Qu MJ: Mutations in acetylcholinesterase genes of Rhopalosiphum padi resistant to organophosphate and insecticides. Genome. 2007 Feb;50(2):172-9. Bioassays showed that the resistant strain used was highly or moderately resistant to pirimicarb, omethoate, and monocrotophos (resistance ratio, 263.8, 53.8, and 17.5, respectively), and showed little resistance to deltamethrin or thiodicarb (resistance ratio, 5.2 and 3.4, respectively). |
6(0,0,0,6) | Details |
| 7447699 | Cambon C, Declume C, Derache R: Foetal and maternal rat brain acetylcholinesterase: isoenzymes changes following insecticidal derivatives poisoning. Arch Toxicol. 1980 Oct;45(4):257-62. Pregnant rats (18th day) were orally given insecticidal carbamates with anticholinesterasic properties: 50 mg/kg carbaryl, 0.1 mg/kg aldicarb, 2.5 mg/kg carbofuran and 20 mg/kg pirimicarb. |
3(0,0,0,3) | Details |
| 15373812 | Andrews MC, Callaghan A, Field LM, Williamson MS, Moores GD: Identification of mutations conferring insecticide-insensitive AChE in the cotton-melon aphid, Aphis gossypii Glover. Insect Mol Biol. 2004 Oct;13(5):555-61. The first of these, S431F (equivalent to F331 in Torpedo californica), is associated with insensitivity to the insecticide pirimicarb in a range of A. gossypii clones. |
2(0,0,0,2) | Details |
| 16704047 | Andersen TH, Tjornhoj R, Wollenberger L, Slothuus T, Baun A: Acute and chronic effects of pulse exposure of Daphnia magna to dimethoate and pirimicarb. Environ Toxicol Chem. 2006 May;25(5):1187-95. The most important new findings in the present study are that short-term (<4 h) pulse exposure of neonates to acetylcholinesterase-inhibiting pesticides caused reproductive damage in D. magna and that repeated-pulse exposure significantly increased mortality in animals that apparently had recovered after a single-pulse exposure. |
1(0,0,0,1) | Details |
| 16470680 | Parker WE, Howard JJ, Foster SP, Denholm I: The effect of insecticide application sequences on the control and insecticide resistance status of the peach-potato aphid, Myzus persicae (Hemiptera:Aphididae), on field crops of potato. Pest Manag Sci. 2006 Apr;62(4):307-15. To ensure adequate aphid populations and to influence the initial resistance status of the aphid population, cultured M. persicae from a clone of known resistance status (esterase R1, kdr heterozygote, non-MACE (modified acetylcholinesterase)) were inoculated into both experiments. Two-spray programmes starting with lambda-cyhalothrin (a pyrethroid insecticide) gave poor control in comparison with programmes starting with pirimicarb (a insecticide) or pirimicarb-containing mixtures. |
1(0,0,0,1) | Details |
| 15378568 | Reuveny H, Cohen E: Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.). Arch Insect Biochem Physiol. 2004 Oct;57(2):92-100. In comparison to acetylcholinesterase (AChE) from susceptible adult codling moth, the enzyme of insects resistant to azinphos-methyl has low affinities (higher K (m) values) to the substrates acetylthiocholine (ATCh) and propionylthiocholine. Of the three carbamates examined, only carbaryl was inhibitory at the mM range while pirimicarb and aldicarb were inactive. |
1(0,0,0,1) | Details |
| 12469775 | Pesando D, Huitorel P, Dolcini V, Angelini C, Guidetti P, Falugi C: Biological targets of pesticides analysed by alteration of developmental events in the Mediterranean sea urchin, Paracentrotus lividus. Mar Environ Res. 2003 Feb;55(1):39-57. The biological effects of Basudin (an organophosphate compound containing 20% Diazinon), Diazinon (Dzn, a thionophosphate), Carbaryl and Pirimicarb (carbamates) on the early phases of sea urchin development were thus investigated. From the gastrulation stage onwards, the main effects were exerted on the rate of primary mesenchyme cells migration, larval size, perioral arm length, and acetylcholinesterase activity distribution, thus deregulating the cholinergic system, which modulates cell-to-cell communication mediated by the signal molecule |
1(0,0,0,1) | Details |
| 10333576 | Rufingier C, Pasteur N, Lagnel J, Martin C, Navajas M: Mechanisms of insecticide resistance in the aphid Nasonovia ribisnigri (Mosley) (Homoptera: Aphididae) from France. Insect Biochem Mol Biol. 1999 Apr;29(4):385-91. Nasonovia ribisnigri, a main pest of salad crops, has developed resistance to various insecticides in southern France, including the pirimicarb and the cyclodiene endosulfan, two insecticides widely used to control this aphid. |
0(0,0,0,0) | Details |