Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name pirimicarb
CAS

Reference List

PubMed Abstract RScore(About this table)
19413913 Lu Y, Gao X: Multiple mechanisms responsible for differential susceptibilities of Sitobion avenae (Fabricius) and Rhopalosiphum padi (Linnaeus) to pirimicarb. Bull Entomol Res. 2009 Dec;99(6):611-7. Epub 2009 May 5.

The addition of synergists DEF, an esterase inhibitor, PBO, a cytochrome P450 monooxygenase inhibitor, and DEM, a glutathione S-transferase inhibitor, resulted in apparent reductions in the differential susceptibilities, suggesting the involvement of the above three detoxification enzymes in the differential susceptibility to pirimicarb between Sitobion avenae and Rhopalosiphum padi.
32(0,1,1,2) Details
8614018 Tanaka H, Hasegawa R, Takesada Y, Ogiso T, Hirose M, Shirai T: Effects of carbamate insecticides in a rat medium-term bioassay for hepatocarcinogens. J Toxicol Environ Health. 1996 Apr 5;47(5):493-8.

Ethiofencarb and pirimicarb, widely used insecticides, were investigated for hepatocarcinogenesis-modifying effects using a medium-term bioassay system for carcinogens.
Development of preneoplastic lesions, glutathione S-transferase placental form-positive foci, in the liver was significantly increased in terms of number receiving 500 ppm ethiofencarb.
1(0,0,0,1) Details
15378568 Reuveny H, Cohen E: Evaluation of mechanisms of azinphos-methyl resistance in the codling moth Cydia pomonella (L.). Arch Insect Biochem Physiol. 2004 Oct;57(2):92-100.


Of the three carbamates examined, only carbaryl was inhibitory at the mM range while pirimicarb and aldicarb were inactive.
0(0,0,0,0) Details