Protein Information

Name thrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

Name cacodylic acid
CAS dimethylarsinic acid

Reference List

PubMed Abstract RScore(About this table)
1159095 Shuman MA, Majerus PW: The perturbation of thrombin binding to human platelets by anions. J Clin Invest. 1975 Oct;56(4):945-50.

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749264 Rotoli B, Miletich JP, Majerus PW: The relation of conductivity to the binding of thrombin to human platelets. Thromb Res. 1978 Dec;13(6):1103-9.

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19167414 Bae ON, Lim KM, Noh JY, Chung SM, Kim SH, Chung JH: Trivalent methylated arsenical-induced phosphatidylserine exposure and apoptosis in platelets may lead to increased thrombus formation. Toxicol Appl Pharmacol. 2009 Sep 1;239(2):144-53. Epub 2009 Jan 6.


DMA (III) also induced PS-exposure with apoptotic features mediated by protein thiol depletion, which resulted in enhanced thrombin generation.
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