Protein Information

Name P gp
Synonyms ABC20; MDR1; ABCB 1; ABCB1; ATP binding cassette sub family B member 1; CD243; CD243 antigen; CLCS…

Compound Information

Name chlorobenzilate
CAS ethyl 4-chloro-α-(4-chlorophenyl)-α-hydroxybenzeneacetate

Reference List

PubMed Abstract RScore(About this table)
16787357 Mayur YC, Padma T, Parimala BH, Chandramouli KH, Jagadeesh S, Gowda NM, Thimmaiah KN: Sensitization of multidrug resistant (MDR) cancer cells to vinblastine by novel acridones: correlation between anti-calmodulin activity and anti-MDR activity. Med Chem. 2006 Jan;2(1):63-77.


Results of the efflux experiment showed that each modulator significantly inhibited the efflux of VLB, suggesting that they may be competitors for P-gp.
2(0,0,0,2) Details