Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
15929901 Roldan-Tapi L, Leyva A, Laynez F, Santed FS: Chronic neuropsychological sequelae of cholinesterase inhibitors in the absence of structural brain damage: two cases of acute poisoning. Environ Health Perspect. 2005 Jun;113(6):762-6.

6(0,0,0,6) Details
15248660 Tilak KS, Veeraiah K, Sastry LV, Rao JV: Effect of fenvalerate technical grade on acetyl cholinesterase activity in Indian bullfrog Haplobatrachus tigerinus (Daudin). J Environ Biol. 2003 Oct;24(4):445-8.

3(0,0,0,3) Details
11748873 Latuszynska J, Luty S, Raszewski G, Tokarska-Rodak M, Przebirowska D, Przylepa E, Haratym-Maj A: Neurotoxic effect of dermally-applied chlorpyrifos and cypermethrin in Wistar rats. Ann Agric Environ Med. 2001;8(2):163-70.


The aim of the study was to evaluate the neurotoxic effect of a dermally-applied mixture of chlorpyrifos and cypermethrin in rats based on cognitive function, activity of the blood cholinesterase and brain acetylcholinesterase, as well as histologic brain examination.
2(0,0,0,2) Details
17370803 Booth LH, Wratten SD, Kehrli P: Effects of reduced rates of two insecticides on enzyme activity and mortality of an aphid and its lacewing predator. J Econ Entomol. 2007 Feb;100(1):11-9.


Cholinesterase (ChE) and glutathione S-transferase (GST) activities in survivors provided a measure of sublethal effects and general fitness.
2(0,0,0,2) Details
14677911 Latuszynska J, Luty S, Raszewski G, Przebirowska D, Tokarska-Rodak M: Neurotoxic effect of dermally applied chlorpyrifos and cypermethrin. Ann Agric Environ Med. 2003;10(2):197-201.


Blood was taken from the heart after 1 day, 1 week, 2 and 3 weeks after the administration of the preparation in order to determine cholinesterase activity in serum, and the brain was taken to evaluate brain cholinesterase activity.
2(0,0,0,2) Details
17239417 Flaskos J, Harris W, Sachana M, Munoz D, Tack J, Hargreaves AJ: The effects of diazinon and cypermethrin on the differentiation of neuronal and glial cell lines. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):172-80. Epub 2006 Dec 15.


Diazinon is a known anti-cholinesterase, but there is limited information regarding its molecular mechanism of action.
1(0,0,0,1) Details
19427694 Tu HT, Silvestre F, Scippo ML, Thome JP, Phuong NT, Kestemont P: Acetylcholinesterase activity as a biomarker of exposure to antibiotics and pesticides in the black tiger shrimp (Penaeus monodon). Ecotoxicol Environ Saf. 2009 Jul;72(5):1463-70. Epub 2009 May 9.


This study aimed to assess the potentiality to use cholinesterase activity (ChE) in black tiger shrimp (Penaeus monodon) as a biomarker of exposure to 2 antibiotics (enrofloxacin, furazolidone) and 2 pesticides (endosulfan, deltamethrin), commonly used in Vietnamese farms.
1(0,0,0,1) Details
11248143 Abou-Donia MB, Goldstein LB, Jones KH, Abdel-Rahman AA, Damodaran TV, Dechkovskaia AM, Bullman SL, Amir BE, Khan WA: Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination. Toxicol Sci. 2001 Apr;60(2):305-14.


On day 45 the animals were sacrificed, and plasma and CNS cholinesterase, and brain choline acetyl transferase, muscarinic and nicotinic acetylcholine receptors were evaluated.
1(0,0,0,1) Details
15273811 Gonzalez Audino P, Vassena C, Barrios S, Zerba E, Picollo MI: Role of enhanced detoxication in a deltamethrin-resistant population of Triatoma infestans (Hemiptera, Reduviidae) from Argentina. Mem Inst Oswaldo Cruz. 2004 May;99(3):335-9. Epub 2004 Jul 19.


These results suggest that degradative esterases (no-cholinesterase) and mono-oxygenases cytochrome p450, play an important role in the resistance to deltamethrin in Salta colony from Argentina.
1(0,0,0,1) Details