Protein Information

Name cAMP dependent protein kinase (protein family or complex)
Synonyms Protein kinase A; cAMP dependent protein kinase; cAMP dependent protein kinases

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
14766180 Nagy G, Reim K, Matti U, Brose N, Binz T, Rettig J, Neher E, Sorensen JB: Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron. 2004 Feb 5;41(3):417-29.

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15337272 Choi JS, Soderlund DM: Cyclosporin A and deltamethrin block the downregulation of Nav1.8 sodium channels expressed in Xenopus oocytes. Neurosci Lett. 2004 Sep 9;367(3):389-93.


The Nav1.8 sodium channel isoform, expressed in sensory neurons and implicated in pain responses, is known to be upregulated in Xenopus oocytes by agents that activate protein kinase A.
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15907653 Chen J, Chen H, Liu R, He J, Song L, Bian Q, Xu L, Zhou J, Xiao H, Dai G, Chang HC, Wang X: Effects of fenvalerate on progesterone production in cultured rat granulosa cells. Reprod Toxicol. 2005 Jul-Aug;20(2):195-202.


These results suggested that multi-site inhibition of progesterone production by fenvalerate including a cAMP-dependent protein kinase pathway and reduction on P450scc gene expression and/or its enzymatic activity in rGCs.
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17721829 Lin YW, Yang HW, Min MY, Chiu TH: Inhibition of associative long-term depression by activation of beta-adrenergic receptors in rat hippocampal CA1 synapses. J Biomed Sci. 2008 Jan;15(1):123-31. Epub 2007 Aug 27.


The inhibitory effect of beta-adrenergic receptors on LTD induction was blocked in slices pretreated with inhibitors of protein kinase A and mitogen-activated protein kinase, suggesting that these signal cascades are downstream effectors following activation of beta-adrenergic receptors.
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