Protein Information

Name calmodulin
Synonyms CALM; CAM; CALM 1; CALM 2; CALM 3; CALM1; CALM2; CALM3…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
16139540 Shin DS, Wilkie MP, Pamenter ME, Buck LT: Calcium and protein phosphatase 1/2A attenuate N-methyl-D-aspartate receptor activity in the anoxic turtle cortex. Comp Biochem Physiol A Mol Integr Physiol. 2005 Sep;142(1):50-7.


Decreases in NMDAR activity during anoxia were also abolished by inclusion of the Ca (2+) chelator -- BAPTA and the calmodulin inhibitor -- calmidazolium.
3(0,0,0,3) Details
16673813 He J, Chen JF, Liu R, Song L, Chang HC, Wang XR: Fenvalerate-induced alterations in calcium homeostasis in rat ovary. . Biomed Environ Sci. 2006 Feb;19(1):15-20.


The total content of calmodulin in ovary was estimated by ELISA at each stage of estrous cycle.
2(0,0,0,2) Details
15363582 He J, Chen J, Liu R, Wang S, Song L, Chang HC, Wang X: Alterations of FSH-stimulated progesterone production and calcium homeostasis in primarily cultured human luteinizing-granulosa cells induced by fenvalerate. Toxicology. 2004 Oct 15;203(1-3):61-8.


Due to calcium and Ca2+ -calmodulin (CaM) system involving gonadotropin-stimulated steroidogenesis by granulosa cells, we then evaluated the effects of fenvalerate on trifluoperazine (TFP)- and verapamil-driven FSH-stimulated P4 production.
2(0,0,0,2) Details
12543454 Takano H, Fukushi H, Morishima Y, Shirasaki Y: Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization. Brain Res. 2003 Feb 7;962(1-2):41-7.

2(0,0,0,2) Details
12065290 Webster CR, Blanch C, Anwer MS: Role of PP2B in cAMP-induced dephosphorylation and translocation of NTCP. . Am J Physiol Gastrointest Liver Physiol. 2002 Jul;283(1):G44-50.


The ability of cAMP to translocate and dephosphorylate NTCP is, in part, dependent on cAMP-mediated increases in cytosolic Ca2+ concentration ([Ca2+]), indicating that a Ca2+/calmodulin-dependent protein phosphatase (PP2B) may be involved.
1(0,0,0,1) Details
14989895 He J, Chen JF, Liu R, Wang YB, Wang XR: [Effect of fenvalerate on the ovarian calcium homeostasis and the serum steroid hormone]. Zhonghua Yu Fang Yi Xue Za Zhi. 2004 Jan;38(1):18-21.


The activity of ovarian Ca (2+)-ATPase and phosphorylase A (P-a) and the contents of calmodulin (CaM) were assessed after a 30-day Fen exposure.
1(0,0,0,1) Details
12785591 Cassano G, Bellantuono V, Ardizzone C, Lippe C: Pyrethroid stimulation of ion transport across frog skin. . Environ Toxicol Chem. 2003 Jun;22(6):1330-4.


Finally, the stimulation by pyrethroids was inhibited by indomethacin and W7 (inhibitors of cyclooxygenases and the Ca2+/calmodulin system, respectively).
1(0,0,0,1) Details
11272206 Zaitsev SV, Appelskog IB, Kapelioukh IL, Yang SN, Kohler M, Efendic S, Berggren PO: Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis. Diabetes. 2001 Feb;50 Suppl 1:S70-6.


Our data show that calcineurin, Ca2+/calmodulin-dependent serine/threonine protein phosphatase 2B, is responsible for the effect of Ca2+ on beta-cell apoptosis.
1(0,0,0,1) Details