| Name | calcineurin (protein family or complex) |
|---|---|
| Synonyms | Calcineurin; Calcineurins; Protein phosphatase 2B |
| Name | pyrethrins |
|---|---|
| CAS | pyrethrins |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17166943 | Ahn HS, Kim SE, Choi BH, Choi JS, Kim MJ, Rhie DJ, Yoon SH, Jo YH, Kim MS, Sung KW, Kwon OJ, Hahn SJ: Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property. Am J Physiol Cell Physiol. 2007 May;292(5):C1714-22. Epub 2006 Dec 13. |
2(0,0,0,2) | Details |
| 14766180 | Nagy G, Reim K, Matti U, Brose N, Binz T, Rettig J, Neher E, Sorensen JB: Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron. 2004 Feb 5;41(3):417-29. We found that constitutive PKA activity was necessary to maintain a large number of vesicles in the release-ready, so-called primed, state, whereas calcineurin (protein phosphatase 2B) activity antagonized this effect. |
1(0,0,0,1) | Details |
| 18429239 | Weiser DC, Shenolikar S: Use of protein phosphatase inhibitors. . Curr Protoc Protein Sci. 2003 May;Chapter 13:Unit 13.10. This unit describes protocols for inhibiting the cellular PP1/PP2A activity with okadaic acid, microcystin-LR, and PP2B/calcineurin and a widely utilized strategy for inhibiting protein tyrosine phosphatases. |
1(0,0,0,1) | Details |
| 18265323 | Weiser DC, Shenolikar S: Use of protein phosphatase inhibitors. . Curr Protoc Mol Biol. 2003 May;Chapter 18:Unit 18.10. This unit describes protocols for inhibiting cellular phosphorylation activity with okadaic acid, microcystin-LR, and PP2B/calcineurin and a widely utilized strategy for inhibiting protein tyrosine phosphatases. |
1(0,0,0,1) | Details |
| 15195093 | Misonou H, Mohapatra DP, Park EW, Leung V, Zhen D, Misonou K, Anderson AE, Trimmer JS: Regulation of ion channel localization and phosphorylation by neuronal activity. Nat Neurosci. 2004 Jul;7(7):711-8. Epub 2004 Jun 13. An influx of Ca (2+) leading to calcineurin activation is both necessary and sufficient for these effects. |
1(0,0,0,1) | Details |
| 11272206 | Zaitsev SV, Appelskog IB, Kapelioukh IL, Yang SN, Kohler M, Efendic S, Berggren PO: Imidazoline compounds protect against interleukin 1beta-induced beta-cell apoptosis. Diabetes. 2001 Feb;50 Suppl 1:S70-6. Our data show that calcineurin, Ca2+/calmodulin-dependent serine/threonine protein phosphatase 2B, is responsible for the effect of Ca2+ on beta-cell apoptosis. |
1(0,0,0,1) | Details |
| 15363394 | Wen Z, Guirland C, Ming GL, Zheng JQ: A CaMKII/calcineurin switch controls the direction of Ca (2+)-dependent growth cone guidance. Neuron. 2004 Sep 16;43(6):835-46. |
2(0,0,0,2) | Details |
| 16644695 | Ranta F, Avram D, Berchtold S, Dufer M, Drews G, Lang F, Ullrich S: Dexamethasone induces cell death in insulin-secreting cells, an effect reversed by exendin-4. Diabetes. 2006 May;55(5):1380-90. Dexamethasone increased PP-2B (calcineurin) activity, an effect abrogated by FK506. |
2(0,0,0,2) | Details |
| 15337272 | Choi JS, Soderlund DM: Cyclosporin A and deltamethrin block the downregulation of Nav1.8 channels expressed in Xenopus oocytes. Neurosci Lett. 2004 Sep 9;367(3):389-93. Perfusion of oocytes with either cyclosporin A or deltamethrin, considered to be diagnostic inhibitors of the protein phosphatase calcineurin, at 10 microM blocked spontaneous downregulation. |
2(0,0,0,2) | Details |
| 18657458 | Araya JE, Cornejo A, Orrego PR, Cordero EM, Cortez M, Olivares H, Neira I, Sagua H, da Silveira JF, Yoshida N, Gonzalez J: Calcineurin B of the human protozoan parasite Trypanosoma cruzi is involved in cell invasion. Microbes Infect. 2008 Jul;10(8):892-900. Epub 2008 May 22. |
2(0,0,0,2) | Details |