Protein Information

Name PP1
Synonyms NPY4 R; PP1; NPY4R; Neuropeptide Y receptor type 4; PPYR 1; PPYR1; Pancreatic polypeptide receptor 1; Y4…

Compound Information

Name pyrethrins
CAS pyrethrins

Reference List

PubMed Abstract RScore(About this table)
15363394 Wen Z, Guirland C, Ming GL, Zheng JQ: A CaMKII/calcineurin switch controls the direction of Ca (2+)-dependent growth cone guidance. Neuron. 2004 Sep 16;43(6):835-46.


A relatively large local Ca2+ elevation preferentially activates CaMKII to induce attraction, while a modest local Ca2+ signal predominantly acts through CaN and phosphatase-1 (PP1) to produce repulsion.
5(0,0,0,5) Details
16139540 Shin DS, Wilkie MP, Pamenter ME, Buck LT: Calcium and protein phosphatase 1/2A attenuate N-methyl-D-aspartate receptor activity in the anoxic turtle cortex. Comp Biochem Physiol A Mol Integr Physiol. 2005 Sep;142(1):50-7.


Okadaic acid and calyculin A, inhibitors of serine/threonine PP1 and PP2A, potentiated NMDAR currents during normoxia and prevented anoxia-mediated attenuation of NMDAR currents.
2(0,0,0,2) Details
18429239 Weiser DC, Shenolikar S: Use of protein phosphatase inhibitors. . Curr Protoc Protein Sci. 2003 May;Chapter 13:Unit 13.10.


This unit describes protocols for inhibiting the cellular PP1/PP2A activity with okadaic acid, microcystin-LR, and PP2B/calcineurin and a widely utilized strategy for inhibiting protein tyrosine phosphatases.
1(0,0,0,1) Details