Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name emamectin
CAS

Reference List

PubMed Abstract RScore(About this table)
17665366 Reyes M, Franck P, Charmillot PJ, Ioriatti C, Olivares J, Pasqualini E, Sauphanor B: Diversity of insecticide resistance mechanisms and spectrum in European populations of the codling moth, Cydia pomonella. Pest Manag Sci. 2007 Sep;63(9):890-902.

Resistances to azinphos-methyl, diflubenzuron, spinosad, tebufenozide and thiacloprid were significantly correlated with mixed-function oxidase activity, while increased glutathione-S-transferase and reduced non-specific esterase activities were correlated with resistance to azinphos-methyl and emamectin, respectively.
81(1,1,1,1) Details
18786259 Olsvik PA, Lie KK, Mykkeltvedt E, Samuelsen OB, Petersen K, Stavrum AK, Lunestad BT: Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.). BMC Pharmacol. 2008 Sep 11;8:16.

The qPCR examinations showed that medication by EB significantly increased the transcription of both HSP70 and glutathione-S-transferase (GST) in liver during a period of 35 days, compared to un-treated fish, possibly via activation of enzymes involved in phase II conjugation of metabolism in the liver.
1(0,0,0,1) Details