Name | glutathione S transferase |
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Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
Name | nitrostyrene |
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CAS | 4-(2-nitro-1-propenyl)phenyl thiocyanate |
PubMed | Abstract | RScore(About this table) | |
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1683476 | Trenga CA, Kunkel DD, Eaton DL, Costa LG: Effect of styrene oxide on rat brain . Neurotoxicology. 1991 Summer;12(2):165-78. Glutathione S-transferase activity in different brain regions, measured using p-nitrostyrene oxide as a substrate, correlated quantitatively with GSH depletion by styrene oxide. |
31(0,1,1,1) | Details |
6812568 | Wackett LP, Gibson DT: Metabolism of xenobiotic compounds by enzymes in cell extracts of the fungus Cunninghamella elegans. Biochem J. 1982 Jul 1;205(1):117-22. Cell extracts of the filamentous fungus Cunninghamella elegans contain epoxide hydrolase (EC 3.3.2.3), glutathione S-transferase (EC 2.5.1.18) and UDP-glucuronosyltransferase (EC 2.4.1.17) activities. Epoxide hydrolase activity was determined with p-nitrostyrene oxide as substrate and was shown to be associated with the 100 000 g pellet obtained from disrupted mycelia. |
3(0,0,0,3) | Details |
3116723 | Monroe DH, Eaton DL: Comparative effects of butylated hydroxyanisole on hepatic in vivo DNA binding and in vitro biotransformation of in the rat and mouse. Toxicol Appl Pharmacol. 1987 Sep 30;90(3):401-9. Control mice had 52 times greater glutathione S-transferase (GST) activity toward the AFB-epoxide, but only 2.6 times greater GST activity toward 1-chloro-2,4-dinitrobenzene (CDNB), compared to that of control rats. Epoxide hydrolase activity toward p-nitrostyrene oxide in mice was only 52% of the activity in rats. |
1(0,0,0,1) | Details |