Name | soluble epoxide hydrolase |
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Synonyms | CEH; Epoxide hydratase; Cytosolic epoxide hydrolase; EPHX 2; EPHX2; Epoxide hydrolase 2; SEH; Soluble epoxide hydrolase… |
Name | nitrostyrene |
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CAS | 4-(2-nitro-1-propenyl)phenyl thiocyanate |
PubMed | Abstract | RScore(About this table) | |
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3218741 | Wixtrom RN, Hammock BD: Continuous spectrophotometric assays for cytosolic epoxide hydrolase. . Anal Biochem. 1988 Oct;174(1):291-9. The assays are applicable to whole tissue homogenates as well as purified enzyme preparations. p-Nitrostyrene oxide and p-nitrophenyl glycidyl ether were also examined and found to be very poor substrates for cytosolic epoxide hydrolase from mouse liver. |
85(1,1,1,5) | Details |
19452475 | Naundorf A, Melzer G, Archelas A, Furstoss R, Wohlgemuth R: Influence of pH on the expression of a recombinant epoxide hydrolase in Aspergillus niger. Biotechnol J. 2009 May;4(5):756-65. The filamentous fungus Aspergillus niger was investigated in relation to its ability to produce a soluble epoxide hydrolase (EH) (E.C. 3.3.2.3) belonging to the microsomal EH family. The production of EH was highest (1000 U/L for p-nitrostyrene oxide) under acidic fermentation conditions (pH value of about 3). |
1(0,0,0,1) | Details |
6185139 | Wang P, Meijer J, Guengerich FP: Purification of human liver cytosolic epoxide hydrolase and comparison to the microsomal enzyme. Biochemistry. 1982 Nov 9;21(23):5769-76. Purified cytosolic TESO hydrolase catalyzes the hydrolysis of cis-8-ethylstyrene 7,8-oxide 10 times more rapidly than does the microsomal enzyme, catalyzes the hydrolysis of TESO and trans-stilbene oxide as rapidly as the microsomal enzyme, but catalyzes the hydrolysis of styrene 7,8-oxide, p-nitrostyrene 7,8-oxide, and naphthalene 1,2-oxide much less effectively than does the microsomal enzyme. |
1(0,0,0,1) | Details |