| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | quinalphos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1675101 | Kusic R, Jovanovic D, Randjelovic S, Joksovic D, Todorovic V, Boskovic B, Jokanovic M, Vojvodic V: HI-6 in man: efficacy of the oxime in poisoning by organophosphorus insecticides. Hum Exp Toxicol. 1991 Mar;10(2):113-8. HI-6 rapidly reactivated human blood acetylcholinesterase inhibited by dimethoxy organophosphorus compounds, while the dimethoxy-inhibited enzyme was mainly resistant to the treatment by HI-6. Although both HI-6 and pralidoxime chloride reactivated the red blood cell cholinesterase in quinalphos-poisoned subjects, the return of enzyme activities was more rapid following the use of HI-6. |
2(0,0,0,2) | Details |
| 15171950 | Srinivas R, Udikeri SS, Jayalakshmi SK, Sreeramulu K: Identification of factors responsible for insecticide resistance in Helicoverpa armigera. Comp Biochem Physiol C Toxicol Pharmacol. 2004 Mar;137(3):261-9. Acetylcholinesterase of resistant larvae was less sensitive to monocrotophos and methyl paraoxon. |
2(0,0,0,2) | Details |
| 9526837 | Gupta A, Gupta A, Shukla GS: Effects of neonatal quinalphos exposure and subsequent withdrawal on free radical generation and antioxidative defenses in developing rat brain. J Appl Toxicol. 1998 Jan-Feb;18(1):71-7. Acetylcholinesterase decreased in the brain and blood after QP exposure but recovered after withdrawal. |
1(0,0,0,1) | Details |
| 10685015 | Srivastava AK, Gupta BN, Bihari V, Mathur N, Srivastava LP, Pangtey BS, Bharti RS, Kumar P: Clinical, biochemical and neurobehavioural studies of workers engaged in the manufacture of quinalphos. Food Chem Toxicol. 2000 Jan;38(1):65-9. Despite similar blood acetylcholinestarase (AChE) levels in both the exposed and control subjects, a significant number of exposed subjects had altered plantar and ankle reflexes. |
1(0,0,0,1) | Details |
| 1375016 | Vasilic Z, Drevenkar V, Rumenjak V, Stengl B, Frobe Z: Urinary excretion of diethylphosphorus metabolites in persons poisoned by quinalphos or chlorpyrifos. Arch Environ Contam Toxicol. 1992 May;22(4):351-7. The most rapid increase in red blood cell acetylcholinesterase activity was noted within 24 h after the first treatment with oximes Pralidoxime and/or HI-6. |
1(0,0,0,1) | Details |
| 4051746 | Durakovic Z, Ivanovic D, Gasparovic V, Gjurasin M: [Simultaneous use of hemodialysis and hemoperfusion in the treatment of poisoning by acetylcholinesterase inhibitors] Arh Hig Rada Toksikol. 1985 Mar;36(1):27-32. |
1(0,0,0,1) | Details |
| 10867365 | Gupta A, Agarwal AK, Shukla1 GS: Effect of quinalphos and cypermethrin exposure on developing blood-brain barrier: role of Environ Toxicol Pharmacol. 2000 Jan 1;8(2):73-78. |
0(0,0,0,0) | Details |
| 8258630 | Jokanovic M: Studies on the delayed neuropathic and anticholinesterase potential of quinalphos (diethyl 2-quinoxalyl phosphorothionate) in hens. J Appl Toxicol. 1993 Sep-Oct;13(5):337-9. Incidence of numerous human poisonings by quinalphos (Ekalux, Bayrusil) in agricultural areas near Belgrade initiated this study on the ability of the compound to inhibit hen brain neuropathy target esterase, acetylcholinesterase and plasma butyrylcholinesterase in vivo. |
81(1,1,1,1) | Details |
| 1509672 | Srivastava MK, Raizada RB, Dikshith TS: Fetotoxic response of technical quinalphos in rats. Vet Hum Toxicol. 1992 Apr;34(2):131-3. A significant inhibition of acetylcholinesterase activity in fetal brain and placenta indicated possible transmigration of quinalphos from dams to fetuses. |
31(0,1,1,1) | Details |
| 10793623 | Sarkar R, Mohanakumar KP, Chowdhury M: Effects of an organophosphate pesticide, quinalphos, on the hypothalamo-pituitary-gonadal axis in adult male rats. J Reprod Fertil. 2000 Jan;118(1):29-38. The effects of chronic sub-lethal doses (7-14 mg kg-1 a day for 15 days) of quinalphos were evaluated in adult male rats for changes in testicular morphology, circulatory concentrations of hormones (LH, FSH, prolactin and activities of acetylcholinesterase (AChE) and angiotensin converting enzyme (ACE) as well as metabolism of biogenic amines and in the hypothalamus and pituitary. |
31(0,1,1,1) | Details |