Protein Information

Name cytosolic malate dehydrogenase
Synonyms Cytosolic malate dehydrogenase; MDH 1; MDH s; MDH1; MDHA; MOR 2; MOR2; Malate dehydrogenase cytoplasmic…

Compound Information

Name oxamate
CAS hexyl 2-(diethylamino)-2-oxoacetate

Reference List

PubMed Abstract RScore(About this table)
11415458 Cortes A, Cascante M, Cardenas ML, Cornish-Bowden A: Relationships between inhibition constants, inhibitor concentrations for 50% inhibition and types of inhibition: new ways of analysing data. Biochem J. 2001 Jul 1;357(Pt 1):263-8.

The type of analysis proposed has been tested experimentally by examining inhibition of lactate dehydrogenase by oxalate (an uncompetitive inhibitor with respect to pyruvate) and oxamate (a competitive inhibitor with respect to pyruvate), and of cytosolic malate dehydrogenase by hydroxymalonate (a mixed inhibitor with respect to oxaloacetate).
81(1,1,1,1) Details