Protein Information

Name PARP
Synonyms COL11A2; PARP; Collagen alpha 2(XI) chain; Collagen alpha 2(XI) chain precursor; Collagen type XI alpha 2; Collagen type XI alpha 2 isoform 1; DFNA13; DFNB53…

Compound Information

Name dipyrithione
CAS 2,2′-dithiobis[pyridine] 1,1′-dioxide

Reference List

PubMed Abstract RScore(About this table)
17464209 Fan Y, Chen H, Qiao B, Luo L, Ma H, Li H, Jiang J, Niu D, Yin Z: Opposing effects of ERK and p38 MAP kinases on HeLa cell apoptosis induced by dipyrithione. Mol Cells. 2007 Feb 28;23(1):30-8.

Suppression of p38 activation by SB203580 reduced the extent of apoptosis of the HeLa cells and also prevented induction of p21, release of cytochrome c, and cleavage of caspase-3 and PARP.
2(0,0,0,2) Details