Protein Information

Name CYP1B1
Synonyms CP1B; CYP1B1; CYPIB 1; CYPIB1; Cytochrome P450 1B1; GLC3A; Cytochrome P450 1B1s

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
17275817 Han EH, Hwang YP, Jeong TC, Lee SS, Shin JG, Jeong HG: Eugenol inhibit 7,12-dimethylbenz [a] anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD (P) H:quinone oxidoreductase. FEBS Lett. 2007 Feb 20;581(4):749-56. Epub 2007 Jan 25.

CYP1A1 and CYP1B1 activity, which catalyze the biotransformation of DMBA, were strongly inhibited by eugenol.
31(0,1,1,1) Details