| Name | UGT2B17 |
|---|---|
| Synonyms | C19 steroid specific UDP glucuronosyltransferase; UDPGT; UDP glucuronosyltransferase 2 family member B17; UDP glucuronosyltransferase 2B17 precursor microsomal; UDP glucuronyltransferase family 2 beta 17; UDP glycosyltransferase 2 family member B17; UDP glycosyltransferase 2 family polypeptide B17; UDP glucuronosyltransferase 2B17… |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9364930 | Belanger G, Beaulieu M, Levesque E, Hum DW, Belanger A: Expression and characterization of a novel UDP-glucuronosyltransferase, UGT2B9, from cynomolgus monkey. DNA Cell Biol. 1997 Oct;16(10):1195-205. Western blot analyses using a polyclonal antibody raised against human UGT2B17 protein also demonstrated expression of homologous UGT2B proteins in monkey tissues. cDNA libraries were constructed from monkey liver and prostate mRNA and a novel UGT2B cDNA, UGT2B9, was isolated from both libraries. The activity of UGT2B9 was tested with over 60 compounds and was demonstrated to be active on C18, C19, and C21 steroids, bile acids, and several xenobiotics including eugenol, 1-naphthol, and |
1(0,0,0,1) | Details |
| 12695357 | Turgeon D, Carrier JS, Chouinard S, Belanger A: Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics. Drug Metab Dispos. 2003 May;31(5):670-6. The higher glucuronidation activity was measured with alizarin (125 pmol x min (-1) x mg protein (-1)), whereas UGT2B17 conjugated eugenol, scopoletin, and galangin with glucuronidation rates of 102.5, 102, and 58 pmol x min (-1) x mg protein (-1), respectively. |
85(1,1,1,5) | Details |
| 8798464 | Beaulieu M, Levesque E, Hum DW, Belanger A: Isolation and characterization of a novel cDNA encoding a human UDP-glucuronosyltransferase active on C19 steroids. J Biol Chem. 1996 Sep 13;271(37):22855-62. UGT2B17 is 95% identical with UGT2B15 and 91% identical with UGT2B8. The major substrates are eugenol > 4-methylumbelliferone > dihydrotestosterone > androstane-3alpha, 17beta-diol (3alpha-diol) > testosterone > androsterone (ADT). |
5(0,0,0,5) | Details |