| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15922856 | Yoo CB, Han KT, Cho KS, Ha J, Park HJ, Nam JH, Kil UH, Lee KT: Eugenol isolated from the essential oil of Eugenia caryophyllata induces a reactive species-mediated apoptosis in HL-60 human promyelocytic leukemia cells. Cancer Lett. 2005 Jul 8;225(1):41-52. Epub 2004 Dec 15. We observed that eugenol transduced the apoptotic signal via ROS generation, thereby inducing mitochondrial permeability transition (MPT), reducing anti-apoptotic protein bcl-2 level, inducing cytochrome c release to the cytosol, and subsequent apoptotic cell death. |
31(0,1,1,1) | Details |
| 10075640 | Furukawa H, Nagasawa T: Novel double bond-transferring hydroxylation reaction involved in microbial metabolism of eugenol. Ann N Y Acad Sci. 1998 Dec 13;864:81-6. The enzyme exhibited a cytochrome c-like absorption spectrum. |
2(0,0,0,2) | Details |
| 16762475 | Ou HC, Chou FP, Lin TM, Yang CH, Sheu WH: Protective effects of eugenol against oxidized LDL-induced cytotoxicity and adhesion molecule expression in endothelial cells. Food Chem Toxicol. 2006 Sep;44(9):1485-95. Epub 2006 Apr 28. Eugneol also inhibited the reactive species (ROS) generation, intracellular accumulation, and the subsequent mitochondrial membrane potential collapse, cytochrome c release and caspase-3 activation induced by oxLDL. |
1(0,0,0,1) | Details |
| 15711935 | Park BS, Song YS, Yee SB, Lee BG, Seo SY, Park YC, Kim JM, Kim HM, Yoo YH: Phospho-ser 15-p53 translocates into mitochondria and interacts with Bcl-2 and Bcl-xL in eugenol-induced apoptosis. Apoptosis. 2005 Jan;10(1):193-200. Phospho-ser 15-p53 physically interacted with Bcl-2 and Bcl-xL in mitochondria and its translocation into mitochondria preceded cytochrome c release and mitochondrial membrane potential (MMP) reduction. |
1(0,0,0,1) | Details |
| 10591845 | Priefert H, Overhage J, Steinbuchel A: Identification and molecular characterization of the eugenol hydroxylase genes (ehyA/ehyB) of Pseudomonas sp. strain HR199. Arch Microbiol. 1999 Dec;172(6):354-63. |
0(0,0,0,0) | Details |