| Name | 5 lipoxygenase |
|---|---|
| Synonyms | 5 lipoxygenase; 5 LO; 5LPG; ALOX 5; ALOX5; Arachidonate 5 lipoxygenase; Arachidonate 5 lipoxygenase variant; LOG 5… |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16216483 | Raghavenra H, Diwakr BT, Lokesh BR, Naidu KA: Eugenol--the active principle from cloves inhibits 5-lipoxygenase activity and in human PMNL cells. Prostaglandins Leukot Essent Fatty Acids. 2006 Jan;74(1):23-7. Epub 2005 Oct 7. |
226(2,4,4,6) | Details |
| 15120715 | Prasad NS, Raghavendra R, Lokesh BR, Naidu KA: Spice phenolics inhibit human PMNL 5-lipoxygenase. . Prostaglandins Leukot Essent Fatty Acids. 2004 Jun;70(6):521-8. eugenol and with one or more phenolic ring and methoxy groups in their structure showed high inhibitory effect, while the non-phenolic spice principle allyl sulfide showed least inhibitory effect on 5-LO. |
122(1,2,3,7) | Details |
| 7945541 | Deigner HP, Wolf G, Ohlenmacher U, Reichling J: 1'-Hydroxyeugenol- and coniferyl derivatives as effective inhibitors of 5-lipoxygenase and Cu (2+)-mediated low density lipoprotein oxidation. Arzneimittelforschung. 1994 Aug;44(8):956-61. |
2(0,0,0,2) | Details |
| 19501497 | Raghavendra RH, Naidu KA: Spice active principles as the inhibitors of human platelet aggregation and biosynthesis. Prostaglandins Leukot Essent Fatty Acids. 2009 Jul;81(1):73-8. Epub 2009 Jun 6. In our previous report we have shown that spices and their active principles inhibit 5-lipoxygenase and also formation of In this study, we report the modulatory effect of spice active principles viz., eugenol, piperine, and allyl sulphide on in vitro human platelet aggregation. |
1(0,0,0,1) | Details |