Name | IL 6 |
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Synonyms | 26 kd protein; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; HGF… |
Name | eugenol |
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CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
PubMed | Abstract | RScore(About this table) | |
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16123706 | Huang FM, Tsai CH, Yang SF, Chang YC: Induction of interleukin-6 and interleukin-8 gene expression by root canal sealers in human osteoblastic cells. J Endod. 2005 Sep;31(9):679-83. Taken together, the activation of IL-6 and IL-8 mRNA gene expression may be one of the pathogenesis of zinc oxide-eugenol based and epoxy resin based root canal sealers-induced periapical inflammation. |
41(0,1,2,6) | Details |
20043298 | Kaur G, Athar M, Alam MS: Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol Carcinog. 2010 Mar;49(3):290-301. To ascertain the molecular mechanisms implicated in the antitumor promoting activity of eugenol, its effect was investigated on markers of tumor promotion and inflammation: ODC activity and iNOS and COX-2 expression, and on levels of proinflammatory cytokines (IL-6, TNF-alpha, and PGE (2)). |
6(0,0,1,1) | Details |
12789158 | Haglund R, He J, Jarvis J, Safavi KE, Spangberg LS, Zhu Q: Effects of root-end filling materials on fibroblasts and macrophages in vitro. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Jun;95(6):739-45. OBJECTIVE: The aim of this study was to investigate the effects of 4 root-end filling materials (mineral trioxide aggregate [MTA], intermediate restorative material [IRM], amalgam, and Retroplast) on cell growth, cell morphology, and cytokine (interleukin [IL] 1beta and IL-6) production in mouse fibroblasts and macrophages. |
2(0,0,0,2) | Details |
20036707 | Yogalakshmi B, Viswanathan P, Anuradha CV: Investigation of antioxidant, anti-inflammatory and DNA-protective properties of eugenol in thioacetamide-induced liver injury in rats. Toxicology. 2010 Feb 9;268(3):204-12. Epub 2009 Dec 29. Markers of liver injury transaminase, transaminase, alkaline phosphatase, gamma-glutamyl transferase and inflammation (myeloperoxidase, tumor necrosis factor-alpha and interleukin-6), oxidative stress (lipid peroxidation indices, protein carbonyl and antioxidant status) and cytochrome P4502E1 activity were assessed. |
1(0,0,0,1) | Details |
19296372 | Rodrigues TG, Fernandes A Jr, Sousa JP, Bastos JK, Sforcin JM: In vitro and in vivo effects of clove on pro-inflammatory cytokines production by macrophages. Nat Prod Res. 2009;23(4):319-26. This work was aimed to investigate the effect in vivo of a water-soluble part of hydroalcoholic extract of clove on pro-inflammatory cytokines (IL-1beta and IL-6) production by macrophages of BALB/c mice. Eugenol was found to be the major component of the clove extract and essential oil, and probably is the causative agent of cytokine inhibition. |
2(0,0,0,2) | Details |
18547706 | Schreiner M, Peiser M, Briechle D, Stahlmann R, Zuberbier T, Wanner R: A new dendritic cell type suitable as sentinel of contact allergens. Toxicology. 2008 Jul 30;249(2-3):146-52. Epub 2008 May 4. The metal allergens and could be detected by measuring Interleukin-6 and macrophage inflammatory protein 1-beta (MIP-1beta, CCL-4) in coculture supernatants. |
2(0,0,0,2) | Details |
9759017 | Koh ET, McDonald F, Pitt Ford TR, Torabinejad M: Cellular response to Mineral Trioxide Aggregate. J Endod. 1998 Aug;24(8):543-7. Media were removed for ELISA analysis of interleukin (IL)-1 alpha, IL-1 beta, IL-6, and macrophage colony-stimulating factor. |
1(0,0,0,1) | Details |
15585374 | Verheyen GR, Schoeters E, Nuijten JM, Van Den Heuvel RL, Nelissen I, Witters H, Van Tendeloo VF, Berneman ZN, Schoeters GE: Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. Toxicol Lett. 2005 Jan 15;155(1):187-94. We here investigated wether genes encoding the interleukins IL-1beta, IL-6 and IL-8, and the chemokines CCL2, CCL3, CCL3L1 and CCL4 are useful markers for sensitization testing in CD34+-progenitor derived dendritic cells (CD34-DC). CD34-DC from at least three donors were exposed during 0.5 up to 24h to the chemical sensitizers sulphate, oxazolone, 2,4-dinitrochlorobenzene (DNCB) and eugenol, and to the irritants (SDS) and benzalkonium sulphate (BC). mRNA expression was evaluated using real-time RT-PCR. |
1(0,0,0,1) | Details |
17118622 | Miyazawa M, Ito Y, Yoshida Y, Sakaguchi H, Suzuki H: Phenotypic alterations and cytokine production in THP-1 cells in response to allergens. Toxicol In Vitro. 2007 Apr;21(3):428-37. Epub 2006 Oct 14. Indeed, all tested allergens, except eugenol (EU), caused significant increased changes in at least four of the analyzed six markers, while non-allergens did not induce any changes. In addition, DNCB and NiSO (4) augmented CD1a expression and production of IL-6, respectively. |
1(0,0,0,1) | Details |