Protein Information

Name CCL3
Synonyms CCL 3; CCL3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; LD78 alpha; LD78ALPHA; MIP 1 alpha Tonsillar lymphocyte LD78 alpha protein…

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
20013178 Nagababu E, Rifkind JM, Boindala S, Nakka L: Assessment of antioxidant activity of eugenol in vitro and in vivo. Methods Mol Biol. 2010;610:165-80.

The protective action of eugenol has been found to be due to interception of secondary radicals derived from ER lipids rather than interfering with primary radicals of CCl (4) (CCl (3)/CCl (3) OO).
81(1,1,1,1) Details
15585374 Verheyen GR, Schoeters E, Nuijten JM, Van Den Heuvel RL, Nelissen I, Witters H, Van Tendeloo VF, Berneman ZN, Schoeters GE: Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. Toxicol Lett. 2005 Jan 15;155(1):187-94.

We here investigated wether genes encoding the interleukins IL-1beta, IL-6 and IL-8, and the chemokines CCL2, CCL3, CCL3L1 and CCL4 are useful markers for sensitization testing in CD34+-progenitor derived dendritic cells (CD34-DC).
CD34-DC from at least three donors were exposed during 0.5 up to 24h to the chemical sensitizers nickel sulphate, oxazolone, 2,4-dinitrochlorobenzene (DNCB) and eugenol, and to the irritants sodium dodecyl sulphate (SDS) and benzalkonium sulphate (BC). mRNA expression was evaluated using real-time RT-PCR.
2(0,0,0,2) Details