| Name | sodium channel (protein family or complex) |
|---|---|
| Synonyms | Sodium channel |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19376653 | Park CK, Kim K, Jung SJ, Kim MJ, Ahn DK, Hong SD, Kim JS, Oh SB: Molecular mechanism for local anesthetic action of eugenol in the rat trigeminal system. Pain. 2009 Jul;144(1-2):84-94. Epub 2009 Apr 18. Interestingly, eugenol shares several pharmacological actions with local anesthetics which include inhibition of voltage-gated sodium channel (VGSC) and activation of transient receptor potential vanilloid subtype 1 (TRPV1). |
81(1,1,1,1) | Details |
| 18218839 | Chung G, Rhee JN, Jung SJ, Kim JS, Oh SB: Modulation of CaV2.3 calcium channel currents by eugenol. . J Dent Res. 2008 Feb;87(2):137-41. We have recently demonstrated the inhibition of Ca (V) 2.2 calcium channel and sodium channel currents to be molecular mechanisms underlying the analgesic effect of eugenol. |
31(0,1,1,1) | Details |
| 16998128 | Park CK, Li HY, Yeon KY, Jung SJ, Choi SY, Lee SJ, Lee S, Park K, Kim JS, Oh SB: Eugenol inhibits currents in dental afferent neurons. . J Dent Res. 2006 Oct;85(10):900-4. Using a whole-cell patch-clamp technique, we investigated the effect of eugenol on voltage-gated sodium channel currents (I (Na)) in rat dental primary afferent neurons identified by retrograde labeling with a fluorescent dye in maxillary molars. |
6(0,0,1,1) | Details |