| Name | lactate dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | LDH; lactate dehydrogenase; lactate dehydrogenases |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8597030 | Reddy AC, Lokesh BR: Effect of and eugenol on iron-induced hepatic toxicity in rats. Toxicology. 1996 Jan 22;107(1):39-45. Oral administration of spice principles, from (30 mg/kg body weight) or eugenol from cloves (100 mg/kg body weight), for 10 days lowered the liver and serum lipid peroxide levels, serum ALAT, ASAT and LDH, enhanced by i.p. injection of iron. |
7(0,0,1,2) | Details |
| 1459632 | Sen P, Maiti PC, Puri S, Ray A, Audulov NA, Valdman AV: Mechanism of anti-stress activity of Ocimum sanctum Linn, eugenol and Tinospora malabarica in experimental animals. Indian J Exp Biol. 1992 Jul;30(7):592-6. RS also caused a generalized increase in enzyme activity and Os, eugenol or Tm effectively lowered the RS-induced elevations in lactate dehydrogenase (LDH) and alkaline phosphatase. |
6(0,0,1,1) | Details |
| 15613789 | Tiku AB, Abraham SK, Kale RK: Eugenol as an in vivo radioprotective agent. J Radiat Res. 2004 Sep;45(3):435-40. Moreover, the level of peroxidative damage and the specific activities of lactate dehydrogenase (LDH) and methylglyoxalase I (Gly I) were observed in the liver of mice treated with eugenol for seven days in comparison to untreated mice. |
6(0,0,1,1) | Details |
| 11199789 | Huang TH, Lii CK, Chou MY, Kao CT: Lactate dehydrogenase leakage of hepatocytes with AH26 and AH Plus sealer treatments. J Endod. 2000 Sep;26(9):509-11. Numerous root canals filling materials are available in the field of dentistry, based on various formulas that contain a variety of different and partly mutagenic components, such as epoxy resin sealers, Ca (OH) 2-based materials, and zinc oxide-eugenol cements. |
3(0,0,0,3) | Details |
| 1427504 | Chan VS, Caldwell J: Comparative induction of unscheduled DNA synthesis in cultured rat hepatocytes by allylbenzenes and their 1'- metabolites. Food Chem Toxicol. 1992 Oct;30(10):831-6. Cytotoxicity was assessed by lactate dehydrogenase leakage. |
1(0,0,0,1) | Details |
| 20104265 | Suanarunsawat T, Devakul Na Ayutthaya W, Songsak T, Thirawarapan S, Poungshompoo S: Antioxidant Activity and Lipid-Lowering Effect of Essential Oils Extracted from Ocimum sanctum L. J Clin Biochem Nutr. 2010 Jan;46(1):52-9. Epub 2009 Dec 29. The results showed that phenyl propanoid compounds including eugenol and methyl eugenol were the major constituents of EO. EO suppressed the high serum lipid profile and atherogenic index as well as serum lactate dehydrogenase and kinase MB subunit without significant effect on high serum levels of aspartate aminotransferase, alanine aminotransferase and alkaline phosphatase in rats fed with HC diet. |
1(0,0,0,1) | Details |
| 11189045 | Hunag TH, Lii CK, Kao CT: Root canal sealers cause cytotoxicity and oxidative damage in hepatocytes. . J Biomed Mater Res. 2001 Mar 5;54(3):390-5. Toxicity was detected by assessing lactate dehydrogenase (LDH) leakage, and oxidative stress was determined by analysis of (GSH) levels. |
1(0,0,0,1) | Details |
| 19775730 | Gencoglu N, Sener G, Omurtag GZ, Tozan A, Uslu B, Arbak S, Helvacioglu D: Comparision of biocompatibility and cytotoxicity of two new root canal sealers. Acta Histochem. 2009 Sep 21. The aim of this study was to investigate the remote organ toxicity and connective tissue reaction of two new root canal sealers ("GuttaFlow ((R))" and "EndoREZ ((R))") and to compare them with zinc oxide eugenol sealer using biochemical and histopathological parameters. Tumor necrosis factor (TNF) and lactate dehydrogenase (LDH) were also assayed in serum samples. |
1(0,0,0,1) | Details |
| 11006409 | Burkey JL, Sauer JM, McQueen CA, Sipes IG: Cytotoxicity and genotoxicity of methyleugenol and related congeners-- a mechanism of activation for methyleugenol. Mutat Res. 2000 Sep 20;453(1):25-33. We were interested in the cytotoxicity and genotoxicity caused by methyleugenol and other alkenylbenzene compounds: (a known hepatocarcinogen), eugenol, and Cytotoxicity was determined by measuring lactate dehydrogenase (LDH) release, while genotoxicity was determined by using the unscheduled DNA synthesis (UDS) assay. |
1(0,0,0,1) | Details |
| 9990138 | Rao M, Kumar MM, Rao MA: In vitro and in vivo effects of phenolic antioxidants against cisplatin-induced nephrotoxicity. J Biochem. 1999 Feb;125(2):383-90. Among phenolic antioxidants, (IG) was found to be more active against cisplatin-induced cytotoxicity in vero cells as well as in rat renal cortical slices than eugenol (EG) and dehydrozingerone (DZ). |
0(0,0,0,0) | Details |