Protein Information

Name beta adrenoceptor (protein family or complex)
Synonyms Beta adrenoceptor; Beta adrenoceptor; Beta adrenergic receptor; Beta adrenergic receptors; Beta adrenoceptor; Beta adrenoceptors; Beta adrenoceptors

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
10413061 Huang YC, Wu BN, Lin YT, Chen SJ, Chiu CC, Cheng CJ, Chen IJ: Eugenodilol: a third-generation beta-adrenoceptor blocker, derived from eugenol, with alpha-adrenoceptor blocking and beta2-adrenoceptor agonist-associated vasorelaxant activities. J Cardiovasc Pharmacol. 1999 Jul;34(1):10-20.
34(0,1,1,4) Details
10440531 Lin YT, Wu BN, Horng CF, Huang YC, Hong SJ, Lo YC, Cheng CJ, Chen IJ: Isoeugenolol: a selective beta1-adrenergic antagonist with tracheal and vascular smooth muscle relaxant properties. Jpn J Pharmacol. 1999 Jun;80(2):127-36.


Furthermore, the binding characteristics of isoeugenolol and various beta-adrenoceptor antagonists were evaluated in [3H] CGP-12177 binding to rat ventricle, lung and interscapular brown adipose tissue (IBAT) membranes.
1(0,0,0,1) Details
18247158 Yeh JL, Liou SF, Chang YP, Lin SW, Liu TS, Wu BN, Chen IJ, Wu JR: Isoeugenodilol inhibits smooth muscle cell proliferation and neointimal thickening after balloon injury via inactivation of ERK1/2 pathway. J Biomed Sci. 2008 May;15(3):375-89. Epub 2008 Feb 5.


The purpose of this study was to determine the efficacy and the possible mechanism of action of the synthesized drug isoeugenodilol (a new third-generation beta-adrenoceptor blocker) on the growth factor-induced proliferation of cultured rat vascular smooth muscle cells (VSMCs) and neointimal formation in a rat carotid arterial balloon injury model.
1(0,0,0,1) Details