Protein Information

Name CCL4
Synonyms ACT2; Lag1; SCYA 2; SCYA2; AT744.1; Act2; CCL4; G 26…

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
8205227 Nagababu E, Lakshmaiah N: Inhibition of microsomal lipid peroxidation and monooxygenase activities by eugenol. Free Radic Res. 1994 Apr;20(4):253-66.

In the present study, we examined the effect of eugenol on microsomal mixed function oxidase mediated peroxidation using Fe+3-ADP-NADPH, carbon tetrachloride (CCL4)-NADPH and cumene hydroperoxide (CumOOH) systems.
81(1,1,1,1) Details
15585374 Verheyen GR, Schoeters E, Nuijten JM, Van Den Heuvel RL, Nelissen I, Witters H, Van Tendeloo VF, Berneman ZN, Schoeters GE: Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. Toxicol Lett. 2005 Jan 15;155(1):187-94.

We here investigated wether genes encoding the interleukins IL-1beta, IL-6 and IL-8, and the chemokines CCL2, CCL3, CCL3L1 and CCL4 are useful markers for sensitization testing in CD34+-progenitor derived dendritic cells (CD34-DC).
CD34-DC from at least three donors were exposed during 0.5 up to 24h to the chemical sensitizers nickel sulphate, oxazolone, 2,4-dinitrochlorobenzene (DNCB) and eugenol, and to the irritants sodium dodecyl sulphate (SDS) and benzalkonium sulphate (BC). mRNA expression was evaluated using real-time RT-PCR.
2(0,0,0,2) Details
18547706 Schreiner M, Peiser M, Briechle D, Stahlmann R, Zuberbier T, Wanner R: A new dendritic cell type suitable as sentinel of contact allergens. Toxicology. 2008 Jul 30;249(2-3):146-52. Epub 2008 May 4.


The metal allergens nickel and cobalt could be detected by measuring Interleukin-6 and macrophage inflammatory protein 1-beta (MIP-1beta, CCL-4) in coculture supernatants.
1(0,0,0,1) Details