Protein Information

Name H:quinone oxidoreductase
Synonyms Diaphorase; DHQU; DIA 4; DIA4; DT diaphorase; DTD; Diaphorase (NADH/NADPH); Diaphorase (NADH/NADPH) (cytochrome b 5 reductase)…

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
17275817 Han EH, Hwang YP, Jeong TC, Lee SS, Shin JG, Jeong HG: Eugenol inhibit 7,12-dimethylbenz [a] anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD (P) H:quinone oxidoreductase. FEBS Lett. 2007 Feb 20;581(4):749-56. Epub 2007 Jan 25.
112(1,2,2,2) Details
8406240 Rompelberg CJ, Verhagen H, van Bladeren PJ: Effects of the naturally occurring alkenylbenzenes eugenol and trans-anethole on drug-metabolizing enzymes in the rat liver. Food Chem Toxicol. 1993 Sep;31(9):637-45.

DT-diaphorase (DTD) activity was only significantly enhanced in the liver cytosol of rats treated with trans-anethole at 250 mg/kg body weight.
1(0,0,0,1) Details