Protein Information

Name ICRF
Synonyms ICRF; P19; PSP; PTP; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine 1 alpha; Lithostathine 1 alpha precursor…

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
16595588 Maralhas A, Monteiro A, Martins C, Kranendonk M, Laires A, Rueff J, Rodrigues AS: Genotoxicity and endoreduplication inducing activity of the food flavouring eugenol. Mutagenesis. 2006 May;21(3):199-204. Epub 2006 Apr 4.

Both eugenol and ICRF-193 were also assayed for inhibition of topoisomerase II, and both showed a dose-dependent inhibitory effect, with ICRF-193 being a more potent inhibitor.
82(1,1,1,2) Details