| Name | xanthine oxidase |
|---|---|
| Synonyms | XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase… |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19387769 | Murata K, Nakao K, Hirata N, Namba K, Nomi T, Kitamura Y, Moriyama K, Shintani T, Iinuma M, Matsuda H: Hydroxychavicol: a potent xanthine oxidase inhibitor obtained from the leaves of betel, Piper betle. J Nat Med. 2009 Jul;63(3):355-9. Epub 2009 Apr 22. |
3(0,0,0,3) | Details |
| 11062707 | Okada N, Satoh K, Atsumi T, Tajima M, Ishihara M, Sugita Y, Yokoe I, Sakagami H, Fujisawa S: Radical modulating activity and cytotoxic activity of synthesized eugenol-related compounds. Anticancer Res. 2000 Sep-Oct;20(5A):2955-60. The ability of nine -related compounds to scavenge O2- (generated by the -xanthine oxidase reaction) was compared with their radical generation and cytotoxic activity. |
1(0,0,0,1) | Details |
| 11834609 | Chang MC, Uang BJ, Wu HL, Lee JJ, Hahn LJ, Jeng JH: Inducing the cell cycle arrest and apoptosis of oral KB carcinoma cells by hydroxychavicol: roles of and reactive species. Br J Pharmacol. 2002 Feb;135(3):619-30. HC (0.02 - 2 microM) was also able to trap radicals generated by a /xanthine oxidase system with 38 - 94% of inhibition. |
1(0,0,0,1) | Details |
| 7548177 | Ko FN, Liao CH, Kuo YH, Lin YL: Antioxidant properties of demethyldiisoeugenol. Biochim Biophys Acta. 1995 Sep 14;1258(2):145-52. It also scavenged generated by /xanthine oxidase and peroxyl radical (ROO.) derived from 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH) in aqueous system with a stoichiometric factor of 1.3 +/- 0.2. |
1(0,0,0,1) | Details |
| 9568113 | Satoh K, Sakagami H, Yokoe I, Kochi M, Fujisawa S: Interaction between eugenol-related compounds and radicals. Anticancer Res. 1998 Jan-Feb;18(1A):425-8. Their ability to scavenge the (O2-), generated by and xanthine oxidase reaction, was in the order of eugenol > bis-eugenol > BHA > bis-BHA. |
1(0,0,0,1) | Details |
| 9046022 | Nagababu E, Lakshmaiah N: Inhibition of xanthine oxidase--iron mediated lipid peroxidation by eugenol in liposomes. Mol Cell Biochem. 1997 Jan;166(1-2):65-71. |
112(1,2,2,2) | Details |
| 8006231 | Jeng JH, Hahn LJ, Lu FJ, Wang YJ, Kuo MY: Eugenol triggers different pathobiological effects on human oral mucosal fibroblasts. J Dent Res. 1994 May;73(5):1050-5. In contrast, eugenol at a concentration less than 1 mmol/L might protect cells from the genetic attack of reactive species via inhibition of xanthine oxidase activity and lipid peroxidation. |
88(1,1,2,3) | Details |
| 9147382 | Wie MB, Won MH, Lee KH, Shin JH, Lee JC, Suh HW, Song DK, Kim YH: Eugenol protects neuronal cells from excitotoxic and oxidative injury in primary cortical cultures. Neurosci Lett. 1997 Apr 4;225(2):93-6. Oxidative neuronal injury induced by /xanthine oxidase was also significantly reduced (75-90%) by eugenol (100- 300 microM) addition. |
87(1,1,2,2) | Details |
| 8394839 | Krishnakantha TP, Lokesh BR: Scavenging of anions by spice principles. Indian J Biochem Biophys. 1993 Apr;30(2):133-4. The anions, as measured by nitrobluetetrazolium (NBT) reduction in -xanthine oxidase system, were inhibited by superoxide dismutase, spice principles eugenol (cloves) and (cumin), antioxidants, butylated toluene and butylated hydroxyanisole in a dose-dependent manner. |
81(1,1,1,1) | Details |
| 8267655 | Rajakumar DV, Rao MN: Dehydrozingerone and as inhibitors of lipid peroxidation and as free radical scavengers. Biochem Pharmacol. 1993 Dec 3;46(11):2067-72. was potent in scavenging generated by the -xanthine oxidase system, whereas eugenol was found to inhibit xanthine oxidase. |
81(1,1,1,1) | Details |
| 7845373 | Reddy AC, Lokesh BR: Studies on the inhibitory effects of and eugenol on the formation of reactive species and the oxidation of ferrous iron. Mol Cell Biochem. 1994 Aug 17;137(1):1-8. Both and eugenol inhibited generation in -xanthine oxidase system to an extent of 40% and 50% at concentrations of 75 microM and 250 microM respectively. |
81(1,1,1,1) | Details |
| 11576616 | Kong LD, Abliz Z, Zhou CX, Li LJ, Cheng CH, Tan RX: Glycosides and xanthine oxidase inhibitors from Conyza bonariensis. Phytochemistry. 2001 Oct;58(4):645-51. Fractionation of the xanthine oxidase inhibitory extract of Conyza bonariensis afforded three glycosides, in addition to nine known compounds including amyrin, beta-sitostero1 daucosterol, 3--5-methoxybenzoic acid, eugenol 4-O-glucopyranoside, and and takakin 8-O- |
33(0,1,1,3) | Details |
| 16756370 | Trevisan MT, Vasconcelos Silva MG, Pfundstein B, Spiegelhalder B, Owen RW: Characterization of the volatile pattern and antioxidant capacity of essential oils from different species of the genus Ocimum. J Agric Food Chem. 2006 Jun 14;54(12):4378-82. O. sanctum), were evaluated using a high-performance liquid chromatography-based /xanthine oxidase and the DPPH assays. Antioxidant capacity was positively correlated (r = 0.92, p < 0.05) with a high proportion of compounds possessing a phenolic ring such as eugenol, while a strong negative correlation (r = -0.77, p > 0.1) with other major volatiles was observed. |
2(0,0,0,2) | Details |