| Name | Lipoxygenase (protein family or complex) |
|---|---|
| Synonyms | arachidonate lipoxygenase; arachidonate lipoxygenases; lipoxygenase; lipoxygenases |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8596779 | Naidu KA: Eugenol--an inhibitor of lipoxygenase-dependent lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids. 1995 Nov;53(5):381-3. |
162(2,2,2,2) | Details |
| 19251422 | Sadeghian H, Attaran N, Jafari Z, Saberi MR, Pordel M, Riazi MM: Design and synthesis of esters as 15-lipoxygenase inhibitors and SAR comparative studies of them. Bioorg Med Chem. 2009 Mar 15;17(6):2327-35. Epub 2009 Feb 13. A group of esters were designed, synthesized and evaluated as potential inhibitors of soybean 15-lipoxygenase (SLO) on the basis of eugenol and esteragol structures. |
32(0,1,1,2) | Details |
| 19157886 | Seyedi SM, Jafari Z, Attaran N, Sadeghian H, Saberi MR, Riazi MM: Design, synthesis and SAR studies of 4-allyoxyaniline amides as potent 15-lipoxygensae inhibitors. Bioorg Med Chem. 2009 Feb 15;17(4):1614-22. Epub 2009 Jan 6. A group of 4-allyloxyaniline amides 5a-o were designed, synthesized and evaluated as potential inhibitors of soybean 15-lipoxygenase (SLO) on the basis of eugenol and esteragol structures. |
31(0,1,1,1) | Details |
| 18824159 | Cho JS, Kim TH, Lim JM, Song JH: Effects of eugenol on Na+ currents in rat dorsal root ganglion neurons. . Brain Res. 2008 Dec 3;1243:53-62. Epub 2008 Sep 19. It inhibits pro-inflammatory mediators including synthase, cyclooxygenase and lipoxygenase. |
1(0,0,0,1) | Details |
| 17998164 | Sadeghian H, Seyedi SM, Saberi MR, Arghiani Z, Riazi M: Design and synthesis of eugenol derivatives, as potent 15-lipoxygenase inhibitors. Bioorg Med Chem. 2008 Jan 15;16(2):890-901. Epub 2007 Oct 12. |
31(0,1,1,1) | Details |
| 7945541 | Deigner HP, Wolf G, Ohlenmacher U, Reichling J: 1'-Hydroxyeugenol- and coniferyl derivatives as effective inhibitors of 5-lipoxygenase and Cu (2+)-mediated low density lipoprotein oxidation. Arzneimittelforschung. 1994 Aug;44(8):956-61. 1'-Hydroxyeugenol- and epoxy-Z-coniferyl esters from Coreopsis species as well as synthetic derivatives of these natural compounds were examined as lipoxygenase inhibitors and as LDL (low density lipoprotein)-stabilizing agents. |
1(0,0,0,1) | Details |
| 19580014 | Thobunluepop P, Pan-in W, Pawelzik E, Vearasilp S: The perspective effects of various seed coating substances on rice seed variety Khao Dawk Mali 105 storability II: the case study of chemical and biochemical properties. Pak J Biol Sci. 2009 Apr 1;12(7):574-81. The aim of this study was to investigate the effects of seed coating substances; chemical fungicide (CA) and biological fungicide polymers -lignosulphonate polymer (CL) and eugenol incorporated into -lignosulphonate polymer (E+CL)] on chemical and biochemical changes of rice seeds cv. After 12 months storage, protein content decreased accompanied by declined of lipid content, increased free fatty acids and activated lipoxygenase enzyme. |
1(0,0,0,1) | Details |
| 17263464 | Li Z, Wang X, Chen F, Kim HJ: Chemical changes and overexpressed genes in sweet basil (Ocimum basilicum L.) upon methyl jasmonate treatment. J Agric Food Chem. 2007 Feb 7;55(3):706-13. Particularly, eugenol and linalool increased by 56 and 43%, respectively. Sequencing of these cDNA clones followed by BLAST searching revealed six unique transcripts displaying high similarities to the known enzymes and peptide, that is, lipoxygenase (LOX), 4-hydroxylase (C4H), prephenate dehydrogenase (PDH), polyphenol oxidase (PPO), acid phosphatase (APase), and pentatricopeptide repeat (PPR), which play significant roles in the formation of secondary metabolites in sweet basil. |
1(0,0,0,1) | Details |