Protein Information

Name NF E2
Synonyms Leucine zipper protein NF E2; NF E2; NFE 2; NFE2; P45 NF E2; Transcription factor NF E2 45 kDa subunit; p45; Transcription factor NF E2 45 kDa subunits…

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
17275817 Han EH, Hwang YP, Jeong TC, Lee SS, Shin JG, Jeong HG: Eugenol inhibit 7,12-dimethylbenz [a] anthracene-induced genotoxicity in MCF-7 cells: Bifunctional effects on CYP1 and NAD (P) H:quinone oxidoreductase. FEBS Lett. 2007 Feb 20;581(4):749-56. Epub 2007 Jan 25.

Furthermore, eugenol increased the expression and activity of NAD (P) H:quinone oxidoreductase (QR), a major detoxifying enzyme for DMBA, through NF-E2 related factor2 binding to antioxidant response element in QR gene.		 31(0,1,1,1) Details