| Name | CCL2 |
|---|---|
| Synonyms | CCL 2; MCAF; CCL2; GDCF 2; GDCF 2 HC11; GDCF2; HC11; HSMCR30… |
| Name | eugenol |
|---|---|
| CAS | 2-methoxy-4-(2-propen-1-yl)phenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15585374 | Verheyen GR, Schoeters E, Nuijten JM, Van Den Heuvel RL, Nelissen I, Witters H, Van Tendeloo VF, Berneman ZN, Schoeters GE: Cytokine transcript profiling in CD34+-progenitor derived dendritic cells exposed to contact allergens and irritants. Toxicol Lett. 2005 Jan 15;155(1):187-94. We here investigated wether genes encoding the interleukins IL-1beta, IL-6 and IL-8, and the chemokines CCL2, CCL3, CCL3L1 and CCL4 are useful markers for sensitization testing in CD34+-progenitor derived dendritic cells (CD34-DC). CD34-DC from at least three donors were exposed during 0.5 up to 24h to the chemical sensitizers sulphate, oxazolone, 2,4-dinitrochlorobenzene (DNCB) and eugenol, and to the irritants (SDS) and benzalkonium sulphate (BC). mRNA expression was evaluated using real-time RT-PCR. |
2(0,0,0,2) | Details |
| 17936526 | Cluzel-Tailhardat M, Bonnet-Duquennoy M, de Queral DP, Vocanson M, Kurfurst R, Courtellemont P, Le Varlet B, Nicolas JF: Chemicals with weak skin sensitizing properties can be identified using low-density microarrays on immature dendritic cells. Toxicol Lett. 2007 Nov 1;174(1-3):98-109. Epub 2007 Sep 5. Thus, DNBS, eugenol and hydroxycitronellal consistently modulated CCR5, CCL27, CCL2 and CCR7, respectively, whereas the CXCL10 gene was regulated by SDS. |
81(1,1,1,1) | Details |