Protein Information

Name aldose reductase
Synonyms ADR; ALDR 1; ALDR1; Aldehyde reductase; AKR1B1; AKR1B1 protein; AR; Aldehyde reductase 1…

Compound Information

Name eugenol
CAS 2-methoxy-4-(2-propen-1-yl)phenol

Reference List

PubMed Abstract RScore(About this table)
12553890 Lee HS: Inhibitory activity of Cinnamomum cassia bark-derived component against rat lens aldose reductase. J Pharm Pharm Sci. 2002 Sep-Dec;5(3):226-30.

However, cinnamyl alcohol, trans -cinnamic acid and eugenol exhibited only weak inhibition against aldose reductase.
116(1,2,2,6) Details
18704333 Jang DS, Yoo NH, Lee YM, Yoo JL, Kim YS, Kim JS: Constituents of the flowers of Erigeron annuus with inhibitory activity on the formation of advanced glycation end products (AGEs) and aldose reductase. Arch Pharm Res. 2008 Jul;31(7):900-4. Epub 2008 Aug 14.

Seven phenolic compounds, caffeic acid (1), 4-hydroxybenzoic acid (2), 4-methoxybenzoic acid (3), protocatechuic acid (4), eugenol O-beta-D: -glucopyranoside (5), 3,6-di-O-feruloylsucrose (6), and 3,5-di-O-caffeoylquinic acid methyl ester (7), were isolated from an EtOAc-soluble partition of the flowers of Erigeron annuus.
2(0,0,0,2) Details