Protein Information

Name C10
Synonyms C10; C10 protein; GRCC10; Gene rich cluster C10; Putative C10 protein; C10 proteins; Gene rich cluster C10s; Putative C10 proteins

Compound Information

Name ryania
CAS

Reference List

PubMed Abstract RScore(About this table)
7982934 Humerickhouse RA, Bidasee KR, Gerzon K, Emmick JT, Kwon S, Sutko JL, Ruest L, Besch HR Jr: High affinity C10-Oeq ester derivatives of ryanodine. J Biol Chem. 1994 Dec 2;269(48):30243-53.

The natural Ryania secondary metabolites ryanodine, dehydroryanodine and esters E and F, all exhibit antithetical concentration-effect curves, indicating both activator and deactivator actions.
5(0,0,0,5) Details
8394996 Humerickhouse RA, Besch HR Jr, Gerzon K, Ruest L, Sutko JL, Emmick JT: Differential activating and deactivating effects of natural ryanodine congeners on the calcium release channel of sarcoplasmic reticulum: evidence for separation of effects at functionally distinct sites. Mol Pharmacol. 1993 Aug;44(2):412-21.

Two novel natural ryanoids from extracts of the wood of Ryania speciosa Vahl were evaluated with sarcoplasmic reticulum (SR) vesicles for their binding affinities and their activating and deactivating effects on Ca2+ release channels.
These compounds were identified by NMR spectroscopy and mass spectroscopy as C9ax-hydroxyryanodine and C8ax-hydroxy-C10-epi-dehydroryanodine, respectively.
1(0,0,0,1) Details