Protein Information

Name DINP
Synonyms DINB protein; DINB 1; DINB1; DINP; DNA polymerase kappa; POLK; POLQ; Polymerase (DNA directed) kappa variant…

Compound Information

Name dimethyl phthalate
CAS dimethyl 1,2-benzenedicarboxylate

Reference List

PubMed Abstract RScore(About this table)
17165549 Niu Z, Ye X, Fang L, Xue Q, Sun Z: [Determination of phthalic acid esters in textiles by solid phase extraction-gas chromatography]. Se Pu. 2006 Sep;24(5):503-7.

A method was established for the simultaneous determination of some phthalic acid esters, namely, dimethyl phthalate (DMP), diethyl phthalate (DEP), dipropyl phthalate (DPrP), dibutyl phthalate (DBP), diamyl phthalate (DAP), dihexyl phthalate (DHP), benzyln-butyl phthalate (BBP), di-(2-ethylhexyl) phthalate (DEHP), dicyclohexyl phthalate (DCHP), di-n-octyl phthalate (DNOP), diisononyl phthalate (DINP) and diisodecyl phthalate (DIDP) in textiles by solid phase extraction (SPE) coupled with gas chromatography (GC).
32(0,1,1,2) Details
20077217 Kwack SJ, Kim KB, Kim HS, Lee BM: Comparative toxicological evaluation of phthalate diesters and metabolites in Sprague-Dawley male rats for risk assessment. J Toxicol Environ Health A. 2009;72(21-22):1446-54.

In order to comparatively assess the systemic toxicity and sperm parameters, nine phthalate diesters, including di (2-ethylhexyl) phthalate (DEHP), di (n-butyl) phthalate (DBP), di-n-octyl phthalate (DnOP), diethyl phthalate (DEP), butylbenzyl phthalate (BBP), dimethyl phthalate (DMP), di-isodecyl phthalate (DIDP), diundecyl phthalate (DUP), and di-isononyl phthalate (DINP), and five phthalate monoesters, including mono (2-ethylhexyl) phthalate (MEHP), monobutyl phthalate (MBuP), monobenzyl phthalate (MBeP), monoethyl phthalate (MEP), monomethyl phthalate (MMP), and phthalic acid (PA) were administered orally to Sprague-Dawley male rats at 250 (phthalate monoesters and PA) or 500 mg/kg body weight (bw)/d (phthalate diesters) for 4 wk.
8(0,0,1,3) Details
11099647 Gray LE Jr, Ostby J, Furr J, Price M, Veeramachaneni DN, Parks L: Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. Toxicol Sci. 2000 Dec;58(2):350-65.

In this regard, we expected that benzyl butyl (BBP) and diethylhexyl (DEHP) phthalate would alter sexual differentiation, while dioctyl tere- (DOTP or DEHT), diethyl (DEP), and dimethyl (DMP) phthalate would not.
We expected that the phthalate mixture diisononyl phthalate (DINP) would be weakly active due to the presence of some phthalates with a 6-7 ester group.
7(0,0,0,7) Details
10641018 Barber ED, Cifone M, Rundell J, Przygoda R, Astill BD, Moran E, Mulholland A, Robinson E, Schneider B: Results of the L5178Y mouse lymphoma assay and the Balb/3t3 cell in vitro transformation assay for eight phthalate esters. J Appl Toxicol. 2000 Jan-Feb;20(1):69-80.

The esters tested were: dimethyl phthalate (DMP), di-n-butyl phthalate (DBP), butyl benzyl phthalate (BBP), di- inverted question markn-hexyl, n-octyl, n-decyl inverted question mark phthalate (610P), di-isononyl phthalate (DINP), di- inverted question markheptyl, nonyl, undecyl inverted question mark phthalate (711P), di-isodecyl phthalate (DIDP) and di-undecyl phthalate (DUP).
6(0,0,1,1) Details