| Name | lactate dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | LDH; lactate dehydrogenase; lactate dehydrogenases |
| Name | dibutyl phthalate |
|---|---|
| CAS | dibutyl 1,2-benzenedicarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2391408 | Fukuoka M, Zhou Y, Tanaka A, Ikemoto I, Machida T: Mechanism of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1990 Aug;10(4):285-93. This was followed by decreases in levels and increases in the activity of lactate dehydrogenase (LDH) and in lactate levels at 12 h, and decreases in the activities of sorbitol dehydrogenase and succinate dehydrogenase on Day 2. |
2(0,0,0,2) | Details |
| 2365410 | Srivastava S, Singh GB, Srivastava SP, Seth PK: Testicular toxicity of di-n-butyl in adult rats: effect on marker enzymes of spermatogenesis. Indian J Exp Biol. 1990 Jan;28(1):67-70. The activity of sorbitol dehydrogenase was found to be significantly decreased while that of lactate dehydrogenase, gamma-glutamyl transpeptidase, beta-glucuronidase, and glucose-6-phosphate dehydrogenase, significantly increased in the animals exposed to 500 and 1000 mg/kg of DBP. |
1(0,0,0,1) | Details |
| 8376724 | Fukuoka M, Kobayashi T, Zhou Y, Hayakawa T: Mechanism of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1993 Jul-Aug;13(4):241-6. A single oral dose of di-n-butyl (DBP) to male rats caused a sloughing of the germ cells at 6 h both with a decrease in the activity of succinate dehydrogenase (SDH) in the Sertoli cells and in the Sertoli-germ connection and with an increase in the activity of lactate dehydrogenase (LDH) in the germ cells. |
1(0,0,0,1) | Details |
| 2988155 | Fariss MW, Reed DJ: Mechanism of chemical-induced toxicity. Toxicol Appl Pharmacol. 1985 Jun 30;79(2):296-306. To determine the role of extracellular Ca2+ in toxic cell death, the viability (leakage of intracellular K+ and lactate dehydrogenase) and total Ca2+ content of isolated hepatocytes incubated in the presence or absence of extracellular Ca2+ were determined during a toxic insult with bromobenzene, ethyl methanesulfonate (EMS), Ca2+ ionophore A23187, and adriamycin (ADR) in combination with 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU). The present study utilized the dibutyl phthalate separation technique which enabled the analysis of only viable hepatocytes for changes in intracellular Ca2+ and K+ content during toxic cell injury. |
1(0,0,0,1) | Details |
| 2128091 | Zhou Y, Fukuoka M, Tanaka A: Mechanisms of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1990 Dec;10(6):447-53. MBP caused decreases in the activities of succinate dehydrogenase in the Sertoli cells and sorbitol dehydrogenase in the germ cells, an increase in the activity of lactate dehydrogenase (LDH) in the germ cells and in the seminiferous lumen and a decrease in testicular iron levels. |
1(0,0,0,1) | Details |
| 2350234 | Srivastava SP, Srivastava S, Saxena DK, Chandra SV, Seth PK: Testicular effects of di-n-butyl (DBP): biochemical and histopathological alterations. Arch Toxicol. 1990;64(2):148-52. The activities of testicular enzymes associated with postmeiotic spermatogenic cells, such as sorbitol dehydrogenase and acid phosphatase, were decreased significantly, while that of lactate dehydrogenase was significantly increased, coincident with degeneration of spermatogenic cells. |
1(0,0,0,1) | Details |