Name | SF 1 |
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Synonyms | AD4BP; Adrenal 4 binding protein; ELP; FTZ 1; FTZ1; FTZF 1; FTZF1; Fushi tarazu factor homolog 1… |
Name | dibutyl phthalate |
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CAS | dibutyl 1,2-benzenedicarboxylate |
PubMed | Abstract | RScore(About this table) | |
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17884934 | Kuhl AJ, Ross SM, Gaido KW: CCAAT/enhancer binding protein beta, but not steroidogenic factor-1, modulates the -induced dysregulation of rat fetal testicular steroidogenesis. Endocrinology. 2007 Dec;148(12):5851-64. Epub 2007 Sep 20. Prolonged in utero exposure of fetal male rats to dibutyl phthalate (DBP) can result in a feminized phenotype characterized by malformed epididymides, hypospadias, cryptorchidism, and retained thoracic nipples, among others. Results demonstrated altered DNase protection at regions mapping to CCAAT/enhancer binding protein beta (c/ebp beta) and steroidogenic factor-1 (SF-1). |
2(0,0,0,2) | Details |
17912698 | Kuhl AJ, Ross SM, Gaido KW: Using a comparative in vivo DNase I footprinting technique to analyze changes in protein-DNA interactions following exposure. J Biochem Mol Toxicol. 2007;21(5):312-22. In vivo footprinting identified three regions of altered DNase digestibility following DBP treatment, and EMSA identified the corresponding transcription factors as SF-1, c/ebp beta, and GATA4. |
2(0,0,0,2) | Details |
15513902 | Kim HS, Kim TS, Shin JH, Moon HJ, Kang IH, Kim IY, Oh JY, Han SY: Neonatal exposure to di (n-butyl) In addition, the expressions of androgen receptor (AR), estrogen receptors (ERs), and steroidogenic factor-1 (SF-1) were also examined in the testes. |
(DBP) alters male reproductive-tract development. J Toxicol Environ Health A. 2004 Dec;67(23-24):2045-60.2(0,0,0,2) | Details |