| Name | sorbitol dehydrogenase |
|---|---|
| Synonyms | L iditol 2 dehydrogenase; SORD; SORD 1; SORD 2; SORD1; SORD2; Sorbitol dehydrogenase; Sorbitol dehydrogenase 1… |
| Name | dibutyl phthalate |
|---|---|
| CAS | dibutyl 1,2-benzenedicarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2365410 | Srivastava S, Singh GB, Srivastava SP, Seth PK: Testicular toxicity of di-n-butyl in adult rats: effect on marker enzymes of spermatogenesis. Indian J Exp Biol. 1990 Jan;28(1):67-70. The activity of sorbitol dehydrogenase was found to be significantly decreased while that of lactate dehydrogenase, gamma-glutamyl transpeptidase, beta-glucuronidase, and glucose-6-phosphate dehydrogenase, significantly increased in the animals exposed to 500 and 1000 mg/kg of DBP. |
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| 2391408 | Fukuoka M, Zhou Y, Tanaka A, Ikemoto I, Machida T: Mechanism of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1990 Aug;10(4):285-93. This was followed by decreases in levels and increases in the activity of lactate dehydrogenase (LDH) and in lactate levels at 12 h, and decreases in the activities of sorbitol dehydrogenase and succinate dehydrogenase on Day 2. |
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| 2128091 | Zhou Y, Fukuoka M, Tanaka A: Mechanisms of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1990 Dec;10(6):447-53. MBP caused decreases in the activities of succinate dehydrogenase in the Sertoli cells and sorbitol dehydrogenase in the germ cells, an increase in the activity of lactate dehydrogenase (LDH) in the germ cells and in the seminiferous lumen and a decrease in testicular iron levels. |
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| 2350234 | Srivastava SP, Srivastava S, Saxena DK, Chandra SV, Seth PK: Testicular effects of di-n-butyl (DBP): biochemical and histopathological alterations. Arch Toxicol. 1990;64(2):148-52. The activities of testicular enzymes associated with postmeiotic spermatogenic cells, such as sorbitol dehydrogenase and acid phosphatase, were decreased significantly, while that of lactate dehydrogenase was significantly increased, coincident with degeneration of spermatogenic cells. |
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| 15562782 | Wang Y, Song L, Zhu Z, Chen J, He J, Liu R, Wang X: [Effect of dibutyl phthalate on the biochemical enzymes and lipid peroxidation in rat testes]. Zhonghua Nan Ke Xue. 2004 Oct;10(10):729-33. After 4-week DBP exposure, while alkaline phosphatase (ALP) activities in the serum revealed an increasing tendency, sorbitol dehydrogenase (SDH) activities were inhibited significantly in both the serum and the testis homogenate at the dosage of 1000 mg/(kg x d) compared with the control group (P < 0.01). |
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