Protein Information

Name bcl 2
Synonyms Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas…

Compound Information

Name dibutyl phthalate
CAS dibutyl 1,2-benzenedicarboxylate

Reference List

PubMed Abstract RScore(About this table)
16137013 Wan WQ, Liu XY, Deng B: [Mechanisms of dibutyl phthalate to purge leukemic cells] . Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004 Feb;29(1):79-80.

The effects of DBP on the protein expression of c-myc and bcl-2 genes of leukemic cells were measured by immunohistochemical assay.
3(0,0,0,3) Details
11719706 Shultz VD, Phillips S, Sar M, Foster PM, Gaido KW: Altered gene profiles in fetal rat testes after in utero exposure to di (n-butyl) phthalate. Toxicol Sci. 2001 Dec;64(2):233-42.


TRPM-2 and bcl-2 protein staining was elevated in GD 21 DBP-exposed Leydig and Sertoli cells.
2(0,0,0,2) Details
15461258 Yu Z, Zhang L, Wu D: [Effects of three environmental estrogens on expression of proliferation and apoptosis-associated genes in PEO4 cells]. Wei Sheng Yan Jiu. 2004 Jul;33(4):404-6.

OBJECTIVE: This study was designed to investigate the molecular mechanisms of proliferation and apoptosis by environmental estrogens (n-4-nonylphenol, NP; Bisphenol A, BisA; Dibutyl Phthalate, DBP) in ovarian cancer PEO4 cells.
After various concentration of NP, BisA and DBP treatment for 72h, the cells were harvested and detected mRNA and protein expression of PCNA, bcl-2 and bax by reverse transcription-polymerase chain reaction and immunohistochemistry, respectively.
2(0,0,0,2) Details