| Name | succinate dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | Succinate dehydrogenase; Succinate dehydrogenases |
| Name | dibutyl phthalate |
|---|---|
| CAS | dibutyl 1,2-benzenedicarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8376724 | Fukuoka M, Kobayashi T, Zhou Y, Hayakawa T: Mechanism of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1993 Jul-Aug;13(4):241-6. Changes in the activity of succinate dehydrogenase and the levels of transferrin and ferritin in the Sertoli and germ cells.. |
2(0,0,0,2) | Details |
| 3969678 | Melnick RL, Schiller CM: Effect of esters on energy coupling and oxidation in rat liver mitochondria. Toxicology. 1985 Jan;34(1):13-27. MEHP was found to act as a non-competitive inhibitor of succinate dehydrogenase activity, with an apparent Ki = 2.4 X 10 (-4) M. |
2(0,0,0,2) | Details |
| 2391408 | Fukuoka M, Zhou Y, Tanaka A, Ikemoto I, Machida T: Mechanism of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1990 Aug;10(4):285-93. This was followed by decreases in levels and increases in the activity of lactate dehydrogenase (LDH) and in lactate levels at 12 h, and decreases in the activities of sorbitol dehydrogenase and succinate dehydrogenase on Day 2. |
1(0,0,0,1) | Details |
| 2128091 | Zhou Y, Fukuoka M, Tanaka A: Mechanisms of testicular atrophy induced by di-n-butyl in rats. J Appl Toxicol. 1990 Dec;10(6):447-53. MBP caused decreases in the activities of succinate dehydrogenase in the Sertoli cells and sorbitol dehydrogenase in the germ cells, an increase in the activity of lactate dehydrogenase (LDH) in the germ cells and in the seminiferous lumen and a decrease in testicular iron levels. |
1(0,0,0,1) | Details |
| 653732 | Tanaka A, Matsumoto A, Yamaha T: Biochemical studies on phthalic esters. Toxicology. 1978 Feb;9(1-2):109-23. Metabolism of dibutyl phthalate (DBP) in animals.. DBP was found to be a strong inhibitor for the succinate dehydrogenase of rat liver. |
1(0,0,0,1) | Details |
| 7140696 | Melnick RL, Schiller CM: Mitochondrial toxicity of esters. Environ Health Perspect. 1982 Nov;45:51-6. The effects of mono- and dibutyl phthalate and mono- and di (2-ethylhexyl) on energy-dependent K+ uptake, respiration rates, and cytochrome c reductase activities of isolated rat liver mitochondria were evaluated. It is concluded that esters affect mitochondrial activities by altering the permeability properties of the inner membrane and by inhibiting succinate dehydrogenase activity. |
1(0,0,0,1) | Details |