Name | SDCN |
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Synonyms | N Syndecan; SDC 3; SDC3; SDCN; SYND 3; SYND3; Syndecan 3; Syndecan neural type… |
Name | strychnine |
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CAS | strychnidin-10-one |
PubMed | Abstract | RScore(About this table) | |
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12803134 | Wang DS, Zhu HL, Li JS: glycine receptors in the rat sacral dorsal commissural neurons. Int J Neurosci. 2003 Mar;113(3):293-305. The results indicate that beta-ALA activates the strychnine-sensitive glycine receptors in the SDCN neurons, and suggest that beta-ALA may act as a functional neurotransmitter in the mammalian SDCN. |
acts on 82(1,1,1,2) | Details |
9593814 | Wang DS, Xu TL, Pang ZP, Li JS, Akaike N: activated currents in the rat sacral dorsal commissural neurons. Brain Res. 1998 May 4;792(1):41-7. The results indicate that both Tau and Gly act on a strychnine-sensitive site to open the same Cl- channels in the SDCN neurons, and suggest that Tau may act as a functional neurotransmitter in the mammalian SDCN. |
-7(0,0,1,2) | Details |
11498962 | Wang DS, Xu TL, Li JS: Modulation of -activated currents by substance P in rat sacral dorsal commissural neurons. Sheng Li Xue Bao. 1999 Aug;51(4):361-70. The modulatory effect of substance P (SP) on strychnine-sensitive (Gly) response was examined in neurons acutely dissociated from the rat sacral dorsal commissural nucleus (SDCN) using nystatin perforated patch recording configuration under voltage-clamp conditions. |
6(0,0,1,1) | Details |
10189117 | Xu TL: neurons from the rat sacral dorsal commissural nucleus. J Auton Nerv Syst. 1999 Feb 15;75(2-3):156-63. The electrophysiological and pharmacological properties of -activated Cl- currents (IGABA) were investigated in enzymatically dissociated rat sacral dorsal commissural nucleus (SDCN) neurons using the nystatin perforated patch recording configuration under voltage-clamp conditions. Bicuculline (BIC) and strychnine (STR) antagonized the IGABA in a concentration-dependent manner. |
-induced responses in acutely dissociated 4(0,0,0,4) | Details |
10841452 | Wang DS, Xu TL, Li JS: activated currents on the same neurons in rat spinal cord. J Hirnforsch. 1999;39(4):531-7. The electrophysiological and pharmacological properties of - and (Gly)-induced responses were investigated in neurons acutely dissociated from the rat sacral dorsal commissural nucleus (SDCN) using the nystatin perforated patch recording configuration under voltage-clamp conditions. Bicuculline (BIC) and strychnine (STR) suppressed I and I (Gly) in a concentration-dependent manner, although they have different affinities for and Gly. potentiated both I and I (Gly) via intracellular protein kinase C on the same neurons. |
potentiates - and -2(0,0,0,2) | Details |
11367678 | Wang DS, Xu TL, Pang ZP, Li JS: [Enhancement of activated whole-cell currents by in rat sacral dorsal commissural neurons]. Sheng Li Xue Bao. 1998 Dec;50(6):656-62. Using nystatin-perforated whole-cell recording configuration, the modulatory effect of on (Tau)-activated current (ITau) was investigated in neurons dissociated from the rat sacral dorsal commissural nucleus (SDCN). The results are as follows: (1) Tau acted on strychnine-sensitive (Gly) receptors and elicited inward currents at a holding potential (VH) of -40 mV in SDCN neurons; (2) in a range of 0.01 to 100 mumol/L, 5-HT enhanced ITau in a concentration-dependent manner; (3) both the reversal potential of Tau and the binding affinity of Tau to Gly receptor were not affected by (4) when the neurons were loaded with 3 mumol/L chelerythrine, application of 1 mumol/L 5-HT failed to enhance ITau. |
-2(0,0,0,2) | Details |