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Tapia JC, Mentis GZ, Navarrete R, Nualart F, Figueroa E, Sanchez A, Aguayo LG: Early expression of glycine and GABA (A) receptors in developing spinal cord neurons. Neuroscience. 2001;108(3):493-506.
Further evidence for functional synaptic activity was provided by the detection of co-localization of gephyrin and synaptophysin at 5 DIV using confocal microscopy. The use of various receptor antagonists (strychnine, bicuculline, DL-2-amino-5-phosphonovalerate [APV], 6-cyano-7-nitroquinoxaline-2,3-dione [CNQX]) revealed that this activity was predominantly glycinergic, and to a smaller extent, GABAergic. |
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