| Name | P10 |
|---|---|
| Synonyms | CGI 102; p10; EXOSC 3; EXOSC3; Exosome complex exonuclease RRP40; Exosome component 3; Exosome component Rrp40; RP11 3J10.8… |
| Name | strychnine |
|---|---|
| CAS | strychnidin-10-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16510772 | Sebe JY, van Brederode JF, Berger AJ: Inhibitory synaptic transmission governs inspiratory motoneuron synchronization. J Neurophysiol. 2006 Jul;96(1):391-403. Epub 2006 Mar 1. Bath application of GABAA and GlyR antagonists significantly reduced oscillation power in neonates (P0-P6) and juveniles (P7-P10) and increased peak integrated activity in both age groups. |
2(0,0,0,2) | Details |
| 19720114 | Cooke JE, Mathers DA, Puil E: Isovaline causes inhibition by increasing conductance in thalamic neurons. Neuroscience. 2009 Dec 15;164(3):1235-43. Epub 2009 Aug 28. In this paper, we examined the possibility that isovaline inhibits neurons by activating strychnine (Str)-sensitive (A) receptors in ventrobasal thalamus. Sagittal brain sections containing ventrobasal nuclei were prepared from P10-P15 rats. |
1(0,0,0,1) | Details |
| 10627581 | Iwasaki S, Momiyama A, Uchitel OD, Takahashi T: Developmental changes in calcium channel types mediating central synaptic transmission. J Neurosci. 2000 Jan 1;20(1):59-65. In fact, Ca (2+) currents directly recorded from the auditory calyceal presynaptic terminal were identified as N-, P/Q-, and R-types at postnatal day 7 (P7) to P10 but became predominantly P/Q-type at P13. |
1(0,0,0,1) | Details |
| 9878874 | Jiang Z, Carlin KP, Brownstone RM: An in vitro functionally mature mouse spinal cord preparation for the study of spinal motor networks. Brain Res. 1999 Jan 23;816(2):493-9. In balb/c mice this stage occurs at around postnatal day 10 (P10). Administration of strychnine elicited synchronous activity bilaterally in lumbar ventral roots. |
1(0,0,0,1) | Details |
| 18234240 | Pedroarena CM, Kamphausen S: Glycinergic synaptic currents in the deep cerebellar nuclei. . Neuropharmacology. 2008 Apr;54(5):784-95. Epub 2007 Dec 23. Here, using whole cell recordings in rat cerebellar slices we demonstrated that after postnatal day 17 (> P17) glycinergic IPSCs can be readily evoked in large deep cerebellar nuclear neurons (DCNs), in the same way as in neonatal DCNs (P7-P10). Spontaneous glycinergic IPSCs were very rare but direct presynaptic depolarization by superfusion with elevated concentration or application of 4-aminopyridine consistently evoked strychnine sensitive IPSCs. |
1(0,0,0,1) | Details |
| 12154171 | Mangin JM, Guyon A, Eugene D, Paupardin-Tritsch D, Legendre P: Functional glycine receptor maturation in the absence of glycinergic input in dopaminergic neurones of the rat substantia nigra. J Physiol. 2002 Aug 1;542(Pt 3):685-97. In neonatal rats (P7-P10), GlyRs exhibited a main conductance state of 100-110 pS with a mean open time of 16 ms. The application of 1 microM gabazine blocked spontaneous or evoked inhibitory synaptic current, while the addition of 1 microM strychnine had no effect, suggesting a lack of functional glycinergic synapses on DA neurones. |
1(0,0,0,1) | Details |
| 16949227 | Xu H, Wang W, Tang ZQ, Xu TL, Chen L: acts as a glycine receptor agonist in slices of rat inferior colliculus. Hear Res. 2006 Oct;220(1-2):95-105. Epub 2006 Sep 1. We investigated in young rats (P10-P14) the effects of on the neuronal responses and synaptic transmissions in the central nucleus of the inferior colliculus (ICC) with a brain slice preparation and with whole-cell patch-clamp recordings. All these effects were reversible after washout and could be blocked by 3 microM strychnine, an antagonist of glycine receptors, but not by 10 microM bicuculline, an antagonist of (A) receptors. |
1(0,0,0,1) | Details |
| 7752562 | Akagi H, Majima T, Uchiyama M: Function and modulation of the cloned glycine receptor channels expressed in Xenopus oocytes. Jpn J Physiol. 1994;44 Suppl 2:S91-6. The alpha 1 mRNA is abundant in the spinal cord and brain stem of mature rats whereas the alpha 2 mRNA was expressed in the tissues during the restricted period from late embryonic (E18) to early postnatal stage (P10). Homomeric glycine receptor channels consisting of alpha 1 or alpha 2 subunit expressed in Xenopus oocytes had an ability to generate Cl- currents, and the currents were suppressed by strychnine, a selective antagonist. |
1(0,0,0,1) | Details |
| 7472446 | Kandler K, Friauf E: Development of glycinergic and glutamatergic synaptic transmission in the auditory brainstem of perinatal rats. J Neurosci. 1995 Oct;15(10):6890-904. Regardless of their polarity, contralaterally elicited PSPs were reversibly blocked by the glycine receptor antagonist strychnine. Their reversal potential shifted dramatically from -21.6 +/- 17.7 mV (E18-P0) to -73.0 +/- 7.1 mV (P10). |
1(0,0,0,1) | Details |