Protein Information

Name UDPGT
Synonyms UDP glucuronosyltransferase 2B28; UDPGT; UDP glucuronosyltransferase 2B28 precursor; UGT2B28; UDP glucuronosyltransferase 2B28 precursors

Compound Information

Name thiazopyr
CAS methyl 2-(difluoromethyl)-5-(4,5-dihydro-2-thiazolyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate

Reference List

PubMed Abstract RScore(About this table)
9007042 Hotz KJ, Wilson AG, Thake DC, Roloff MV, Capen CC, Kronenberg JM, Brewster DW: Mechanism of thiazopyr-induced effects on thyroid hormone homeostasis in male Sprague-Dawley rats. Toxicol Appl Pharmacol. 1997 Jan;142(1):133-42.

Dose-related changes associated with thiazopyr treatment were significant increases in liver weight, thyroid weight, and hepatic T4-UDPGT activity at high doses.
8(0,0,1,3) Details