Protein Information

Name Krox20
Synonyms AT591; CMT4E; CMT1D; EGR 2; EGR2; Early growth response 2 protein; Early growth response protein 2; KROX20…

Compound Information

Name triadimefon
CAS

Reference List

PubMed Abstract RScore(About this table)
17343997 Massa V, Gaudenzi G, Sangiorgio L, Cotelli F, Giavini E: Krox20 is down-regulated following triazole in vitro embryonic exposure: a polycompetitor-based assay. Toxicol Lett. 2007 Mar 30;169(3):196-204. Epub 2007 Jan 30.

In order to analyse Krox20 mRNA levels in rat embryos exposed in vitro to the triazole derivative triadimefon, a semi-quantitative approach utilising the competitive RT-PCR was chosen.
85(1,1,1,5) Details
15913947 Menegola E, Broccia ML, Di Renzo F, Massa V, Giavini E: Study on the common teratogenic pathway elicited by the fungicides triazole-derivatives. Toxicol In Vitro. 2005 Sep;19(6):737-48.

The aim of the present work is to identify if a common pathogenic pathway is detectable also for other molecules of this class of compounds. 9.5 days post coitum (d.p.c.) old rat embryos were exposed in vitro to the teratogenic concentrations of Flusilazole, Triadimefon and Triadimenol and cultured for 24, 48 or 60 h.
The expression and localisation of Hox-b1 and Krox-20 proteins (used as markers for hindbrain segmentation) were evaluated after 24 h of culture.
1(0,0,0,1) Details
16875885 Papis E, Bernardini G, Gornati R, Menegola E, Prati M: Gene expression in Xenopus laevis embryos after Triadimefon exposure. Gene Expr Patterns. 2007 Jan;7(1-2):137-42. Epub 2006 Jun 27.

0(0,0,0,0) Details