Protein Information

Name lanosterol synthase
Synonyms E.C. 5.4.99.7; LSS; Lanosterol synthase; OSC; Oxidosqualene lanosterol cyclase; Oxidosqualene lanosterol cyclase; Lanosterol synthases; Oxidosqualene lanosterol cyclases…

Compound Information

Name tridemorph
CAS tridemorph

Reference List

PubMed Abstract RScore(About this table)
16165233 Hankins EG, Gillespie JR, Aikenhead K, Buckner FS: Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors. Mol Biochem Parasitol. 2005 Nov;144(1):68-75.

In this report, we describe the effects of sterol biosynthesis inhibitors (simvistatin, zaragosic acid, terbinafine, a lanosterol synthase inhibitor, ketoconazole, and tridemorph) on the regulation of two sterol biosynthesis genes and their protein products.
32(0,1,1,2) Details