Protein Information

Name epoxide hydrolase
Synonyms EPHX; EPHX 1; EPHX1; EPHX1 protein; EPOX; Epoxide hydratase; Epoxide hydrolase; Epoxide hydrolase 1…

Compound Information

Name tridiphane
CAS 2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane

Reference List

PubMed Abstract RScore(About this table)
3424374 Magdalou J, Hammock BD: Metabolism of tridiphane (2-(3,5-dichlorophenyl)-2 (2,2,2-trichloroethyl) oxirane) by hepatic epoxide hydrolases and glutathione S-transferases in mouse. Toxicol Appl Pharmacol. 1987 Dec;91(3):439-49.

The transformation of the herbicide tridiphane (Tandem, Dowco 356, 2-(3,5-dichlorophenyl)-2 (2,2,2-trichloroethyl) oxirane by the epoxide-metabolizing enzymes, epoxide hydrolases (EH) and glutathione S-transferases (GST), was investigated in mouse liver microsomes and cytosol.
112(1,2,2,2) Details
3590187 Moody DE, Hammock BD: The effect of tridiphane (2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl) oxirane) on hepatic epoxide-metabolizing enzymes: indications of peroxisome proliferation. Toxicol Appl Pharmacol. 1987 Jun 15;89(1):37-48.

0(0,0,0,0) Details
2043152 Moody DE, Montgomery KA, Ashour MB, Hammock BD: Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes. Biochem Pharmacol. 1991 Jun 1;41(11):1625-37.


The epoxides included the pesticides: heptachlor epoxide, dieldrin, tridiphane, and juvenoid R-20458; the natural products: disparlure, limonin, nomilin, and epoxymethyloleate; the endogenous steroids: lanosterol epoxide, cholesterol-alpha-epoxide, and progesterone epoxide; and the industrial or synthetic epoxides: epichlorohydrin, araldite, trans-stilbene oxide, and 4'-phenylchalcone oxide.
0(0,0,0,0) Details