| Name | glutathione S transferases |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | metolachlor |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16667299 | Dean JV, Gronwald JW, Eberlein CV: Induction of Glutathione S-Transferase Isozymes in Sorghum by Herbicide Antidotes. Plant Physiol. 1990 Feb;92(2):467-473. The results are consistent with the hypothesis that antidotes confer protection against metolachlor injury in sorghum by inducing the de novo synthesis of glutathione S-transferase isozymes which catalyze the detoxification of the herbicide. |
152(1,3,4,7) | Details |
| 9933965 | Cottingham CK, Hatzios KK, Meredith S: Influence of chemical treatments on glutathione S-transferases of maize with activity towards metolachlor and Z Naturforsch C. 1998 Nov-Dec;53(11-12):973-9. The subcellular distribution of glutathione S-transferase (GST) activity extracted from shoots of 3-day-old etiolated seedlings of maize (Zea mays L., Northrup-King 9283 hybrid) and the induction of soluble and membrane-bound GST activity by the safener benoxacor, the herbicide metolachlor and their combination (CGA-180937) were investigated. |
37(0,1,2,2) | Details |
| 18607078 | Cho HY, Kong KH: Study on the biochemical characterization of herbicide detoxification enzyme, glutathione S-transferase. Biofactors. 2007;30(4):281-7. On the other hand, the phi class OsGST enzymes showed high specific activity toward chloroacetanilide herbicides, acetochlor, alachlor and metolachlor. |
2(0,0,0,2) | Details |
| 8278547 | Mauch F, Dudler R: Differential induction of distinct glutathione-S-transferases of wheat by xenobiotics and by pathogen attack. Plant Physiol. 1993 Aug;102(4):1193-201. |
2(0,0,0,2) | Details |
| 9662530 | Gronwald JW, Plaisance KL: Isolation and characterization of glutathione S-transferase isozymes from sorghum. Plant Physiol. 1998 Jul;117(3):877-92. GST A1/A1 exhibited high activity with 1-chloro-2, 4, dinitrobenzene (CDNB) but low activity with the chloroacetanilide herbicide metolachlor. |
2(0,0,0,2) | Details |
| 18380233 | Aly MA, Schroder P: Effect of herbicides on glutathione S-transferases in the earthworm, Eisenia fetida. Environ Sci Pollut Res Int. 2008 Mar;15(2):143-9. The current investigation aims to characterize detoxification enzymes in Eisenia fetida and stress response against two herbicides with different modes of action, namely, fenoxaprop and metolachlor. |
2(0,0,0,2) | Details |
| 12231867 | Fuerst EP, Irzyk GP, Miller KD: Partial Characterization of Glutathione S-Transferase Isozymes Induced by the Herbicide Safener Benoxacor in Maize. Plant Physiol. 1993 Jul;102(3):795-802. Protection from metolachlor injury was closely correlated with GST activity, which was assayed with metolachlor as a substrate, as benoxacor concentration increased from 0.01 to 1 [mu] M. |
2(0,0,0,2) | Details |
| 17669266 | Cho HY, Lee HJ, Kong KH: A phi class glutathione S-transferase from Oryza sativa (OsGSTF5): molecular cloning, expression and biochemical characteristics. J Biochem Mol Biol. 2007 Jul 31;40(4):511-6. The OsGSTF5 also had high activities towards the herbicides alachlor, atrazine and metolachlor. |
2(0,0,0,2) | Details |
| 8278534 | Irzyk GP, Fuerst EP: Purification and characterization of a glutathione S-transferase from benoxacor-treated maize (Zea mays). Plant Physiol. 1993 Jul;102(3):803-10. The enzyme, assayed with metolachlor as a substrate, was purified approximately 200-fold by ammonium precipitation, anion-exchange chromatography on Mono Q resins, and affinity chromatography on S-hexylglutathione agarose from total GST activity present in etiolated shoots. |
2(0,0,0,2) | Details |
| 16538523 | Nutricati E, Miceli A, Blando F, De Bellis L: Characterization of two Arabidopsis thaliana glutathione S-transferases. . Plant Cell Rep. 2006 Sep;25(9):997-1005. Epub 2006 Mar 15. Our results reveal that AtGSTU26 is induced by the chloroacetanilide herbicides alachlor and metolachlor and the safener benoxacor, and after exposure to low temperatures. |
2(0,0,0,2) | Details |
| 18004742 | Perez S, Farkas M, Barcelo D, Aga DS: Characterization of conjugates of chloroacetanilide pesticides using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and liquid chromatography/ion trap mass spectrometry. Rapid Commun Mass Spectrom. 2007;21(24):4017-22. Glutathione S-transferases (GSTs) isolated from maize were used to catalyze the conjugation of with chloroacetanilide herbicides, producing stable conjugates that were structurally characterized using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UPLC/QqToF-MS) and liquid chromatography/ion trap mass spectrometry (LC/IT-MS). Enzyme-mediated dechlorination of alachlor, metolachlor, and propachlor resulted during conjugation as revealed by the mass spectra of the conjugates, which was confirmed by the loss of the isotopic signature and from high accurate mass measurements. |
1(0,0,0,1) | Details |
| 16665913 | O'connell KM, Breaux EJ, Fraley RT: Different Rates of Metabolism of Two Chloroacetanilide Herbicides in Pioneer 3320 Corn. Plant Physiol. 1988 Feb;86(2):359-363. The in vivo rates of uptake and detoxification of alachlor and metolachlor were determined using Pioneer corn 3320 seedlings. Since the initial step in detoxification is conjugation of the chloroacetanilide to the activities of the enzymes responsible for conjugation, the glutathione-S-transferases (GST) were also analyzed in vitro, using crude extracts and the purified GST enzymes. |
1(0,0,0,1) | Details |
| 9561822 | Stamper DM, Tuovinen OH: Biodegradation of the acetanilide herbicides alachlor, metolachlor, and propachlor. Crit Rev Microbiol. 1998;24(1):1-22. This conjugation is mediated by glutathione-S-transferase, which is present in microorganisms, plants, and mammals. |
1(0,0,0,1) | Details |
| 20015538 | White PM, Potter TL, Culbreath AK: Fungicide dissipation and impact on metolachlor aerobic soil degradation and soil microbial dynamics. Sci Total Environ. 2010 Feb 15;408(6):1393-402. Epub 2009 Dec 16. This suggested that the fungicide impacted soil glutathione-S-transferase (GST) activity. |
1(0,0,0,1) | Details |
| 15923336 | Mezzari MP, Walters K, Jelinkova M, Shih MC, Just CL, Schnoor JL: Gene expression and microscopic analysis of Arabidopsis exposed to chloroacetanilide herbicides and explosive compounds. Plant Physiol. 2005 Jun;138(2):858-69. Epub 2005 May 27. In this work, Arabidopsis (Arabidopsis thaliana; ecotype Columbia) seedlings were exposed to 0.6 mm acetochlor (AOC), 2 mm metolachlor (MOC), 0.6 mm 2,4,6-trinitrotoluene (TNT), and 0.3 mm hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). Reverse transcription-PCR established the expression profile of glutathione S-transferases (GSTs) and nitroreductases enzymes. |
1(0,0,0,1) | Details |
| 17592585 | Farkas M, Berry JO, Aga DS: Determination of enzyme kinetics and conjugates of chlortetracycline and chloroacetanilides using liquid chromatography-mass spectrometry. Analyst. 2007 Jul;132(7):664-71. Epub 2007 May 29. Glutathione S-transferases (GSTs) isolated from chlortetracycline (CTC)-treated maize catalyzed the conjugation of (GSH) with CTC, producing stable conjugates that were structurally characterized using liquid chromatography-ion-trap mass spectrometry (LC-IT-MS). The catalytic activity of the CTC-induced GST towards dechlorination of chloroacetanilide herbicides (alachlor, metolachlor and propachlor), which are known to be detoxified in plants via the pathway, was also evaluated in vitro. |
1(0,0,0,1) | Details |