| Name | beta glucosidase |
|---|---|
| Synonyms | CBG; CBG; GLUC; CBGL 1; CBGL1; Cytosolic beta glucosidase; Cytosolic beta glucosidase like protein 1; GBA 3… |
| Name | validamycin |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16377847 | Xue YP, Zheng YG, Shen YC: Preparation of trehalase inhibitor validoxylamine A by biocatalyzed hydrolysis of validamycin A with honeybee (Apis cerana Fabr.) beta-glucosidase. Appl Biochem Biotechnol. 2005 Dec;127(3):157-71. Investigation of the biocatalyzed hydrolysis process from validamycin A to validoxylamine A with beta-glucosidase revealed that both the substrate (validamycin A) and the product (validoxylamine A) inhibited beta-glucosidase activity. |
120(1,2,3,5) | Details |
| 3583921 | Asano N, Yamaguchi T, Kameda Y, Matsui K: Effect of validamycins on glycohydrolases of Rhizoctonia solani. J Antibiot. 1987 Apr;40(4):526-32. It was found that validamycin A is transported into the cell and hydrolyzed therein by a beta-glucosidase yielding validoxylamine A with greater inhibitory activity. |
81(1,1,1,1) | Details |
| 17120091 | Yin Y, Huang W, Chen D: Preparation of validoxylamine A by biotransformation of validamycin A using resting cells of a recombinant Escherichia coli. Biotechnol Lett. 2007 Feb;29(2):285-90. Epub 2006 Nov 22. A gene encoding beta-glucosidase was cloned and over-expressed in Escherichia coli. |
1(0,0,0,1) | Details |
| 7864639 | Kyosseva SV, Kyossev ZN, Elbein AD: Inhibitors of pig kidney trehalase. . Arch Biochem Biophys. 1995 Feb 1;316(2):821-6. Validoxylamine A and validamycin A, two other trehalase inhibitors, showed potent competitive inhibition against purified pig kidney trehalase, with IC50 values of 2.4 x 10 (-9) and 2.5 x 10 (-4) M, respectively. |
0(0,0,0,0) | Details |