Protein Information

Name glutamyl transpeptidase
Synonyms CD224; CD224 antigen; D22S672; D22S732; GGT; GGT 1; GGT1; GGT1 protein…

Compound Information

Name endosulfan
CAS 6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
8588293 Sinha N, Narayan R, Shanker R, Saxena DK: Endosulfan-induced biochemical changes in the testis of rats. Vet Hum Toxicol. 1995 Dec;37(6):547-9.

Decreased sperm counts in the cauda epididymis and reduced intratesticular spermatid counts associated with elevation in the activities of specific testicular marker enzymes (sorbitol dehydrogenase, lactic dehydrogenase, gamma glutamyl transpeptidase, and glucose-6-phosphate dehydrogenase) were seen in all the endosulfan-dosed groups.
31(0,1,1,1) Details
20214973 El-Shenawy NS: Effects of insecticides fenitrothion, endosulfan and abamectin on antioxidant parameters of isolated rat hepatocytes. Toxicol In Vitro. 2010 Mar 7.

The activities of glutathione-S-transferase (GST) and gamma glutamyl transpeptidase (gamma-GT) were more affected by fenitrothion and endosulfan, respectively, indicating an oxidative stress.
13(0,0,2,3) Details
2908437 Blat A, Almar MM, Romero FJ: The effect of two sulphur-containing pesticides, fenitrothion and endosulfan, on glutathione (GSH) content and on GSH S-transferase and gamma-glutamyl transpeptidase activities in midgut gland of the American red crayfish Procambarus clarkii. Drug Metabol Drug Interact. 1988;6(3-4):383-94.
9(0,0,1,4) Details
3387377 Flodstrom S, Warngard L, Hemming H, Fransson R, Ahlborg UG: Tumour promotion related effects by the cyclodiene insecticide endosulfan studied in vitro and in vivo. Pharmacol Toxicol. 1988 Apr;62(4):230-5.

Endosulfan was also studied for enhancement of gamma-glutamyl transpeptidase positive enzyme altered foci incidence in partially hepatectomized, nitrosodiethylamine-initiated male Sprague-Dawley rats.
6(0,0,1,1) Details
19669582 Khan DA, Hashmi I, Mahjabeen W, Naqvi TA: Monitoring health implications of pesticide exposure in factory workers in Pakistan. Environ Monit Assess. 2009 Aug 8.

Plasma cypermethrin, endosulfan, imidacloprid, thiodicarb, carbofuran, and methamidophos levels were found to be higher than allowable daily intake.
Plasma alanine aminotransferase (ALT), aspartate aminotransferase (AST), creatinine, urea, and gamma glutamyltransferase (GGT) were measured on Selectra E auto analyzer.
1(0,0,0,1) Details