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Quistad GB, Staiger LE, Schooley DA: The role of carnitine in the conjugation of acidic xenobiotics. Drug Metab Dispos. 1986 Sep-Oct;14(5):521-5.
The CPCA-carnitine is cleaved enzymatically (carnitine acetyltransferase) more slowly in vitro than are acetyl- and propionylcarnitines, but also slightly more extensively.
Effects of dietary exposure of rats to CPCA were determined by feeding cycloprate (a CPCA precursor) at 5000 ppm and then assaying tissue levels of carnitine. |
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